About NAs
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Nucleoside analogs are a class of compounds structurally similar to natural nucleosides, obtained by modifying
the sugar or base components of the nucleoside. Due to their ability to effectively interfere with DNA or RNA
synthesis, nucleoside analogs hold significant importance in drug development, particularly in antiviral and
anticancer therapies. These compounds can be incorporated into the growing nucleic acid chain, thereby
disrupting the replication process and inhibiting the proliferation of pathogens or cancer cells. By
introducing various chemical modifications to the nucleoside structure, it is possible to design compounds
with specific functionalities or enhanced potency.Learn more
What is NA-DB?
The NA-DB encompasses a comprehensive collection of 9074 nucleoside analogs,
4513 base fragments, and 2608 ribose fragments,
providing detailed information on their chemical structures, physicochemical properties, targets, and biological
activities, and users can also browse cluster information.