| Adenosine A1 receptor |
Ki |
> |
100000.0 |
nM |
Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells |
CHEMBL1153377 |
| Adenosine A2a receptor |
Ki |
= |
9600.0 |
nM |
Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cells |
CHEMBL1153377 |
| Adenosine A2b receptor |
Ki |
> |
30000.0 |
nM |
Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activity |
CHEMBL1153377 |
| Adenosine A3 receptor |
Ki |
> |
100000.0 |
nM |
Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cells |
CHEMBL1153377 |
| Unchecked |
Ki |
= |
49100.0 |
nM |
Displacement of [3H]adenine from adenine 1 receptor in rat brain cortical membrane by liquid scintillation counting |
CHEMBL1156038 |
| Unchecked |
Ki |
= |
100000.0 |
nM |
Displacement of [3H]adenine from adenine 1 receptor in HEK293 cells by liquid scintillation counting |
CHEMBL1156038 |
| Unchecked |
Ratio Ki |
= |
2.0 |
|
Selectivity ratio of Ki for adenine 1 receptor in HEK293 cells to Ki for adenine 1 receptor in rat brain cortical membrane |
CHEMBL1156038 |
| Unchecked |
Inhibition |
= |
57.0 |
% |
Inhibition of [3H]adenine binding to adenine 1 receptor in HEK293 cells at 100 uM by liquid scintillation counting |
CHEMBL1156038 |
| microRNA 21 |
Potency |
= |
16481.6 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Modulators of miRNAs and/or Activators of miR-21. (Class of assay: confirmatory) |
CHEMBL1201862 |
| microRNA 21 |
Potency |
= |
16481.6 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Nuclear factor erythroid 2-related factor 2 |
Potency |
|
14581.0 |
nM |
PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] |
CHEMBL1201862 |
| Unchecked |
Potency |
|
15848.9 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485345, AID485355] |
CHEMBL1201862 |
| ATPase family AAA domain-containing protein 5 |
Potency |
|
2908.1 |
nM |
PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] |
CHEMBL1201862 |
| Plasmodium falciparum |
Potency |
|
928.5 |
nM |
PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] |
CHEMBL1201862 |
| DNA polymerase iota |
Potency |
|
89125.1 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] |
CHEMBL1201862 |
| Unchecked |
Potency |
|
6309.6 |
nM |
PUBCHEM_BIOASSAY: qHTS for inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249, AID540278] |
CHEMBL1201862 |
| Glucagon-like peptide 1 receptor |
Potency |
|
7079.5 |
nM |
PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Glycoprotein hormones alpha chain |
Potency |
|
3162.3 |
nM |
PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Tyrosyl-DNA phosphodiesterase 1 |
Potency |
|
16360.1 |
nM |
PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) |
CHEMBL1201862 |
