| Beta-lactamase AmpC |
Potency |
= |
631.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] |
CHEMBL1201862 |
| DNA polymerase beta |
Potency |
= |
79432.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
6309.6 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485345, AID485355] |
CHEMBL1201862 |
| Chromobox protein homolog 1 |
Potency |
|
89125.1 |
nM |
PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] |
CHEMBL1201862 |
| Plasmodium falciparum |
Potency |
|
13115.4 |
nM |
PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] |
CHEMBL1201862 |
| SN12C |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| MDA-N |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NCI-H23 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| ACHN |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| UO-31 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| HOP-92 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| HL-60 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SF-539 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| DU-145 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Malme-3M |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SK-MEL-5 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| K562 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the K-562 Leukemia cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| A498 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the A498 Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| OVCAR-3 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the OVCAR-3 Ovarian cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| MOLT-4 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MOLT-4 Leukemia cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| HOP-62 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-62 Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| U-251 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the U251 Central Nervous System cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NCI/ADR-RES |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI/ADR-RES Breast cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| OVCAR-8 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the OVCAR-8 Ovarian cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| OVCAR-5 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the OVCAR-5 Ovarian cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| MDA-MB-231 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-231/ATCC Breast cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SNB-19 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SNB-19 Central Nervous System cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| TK-10 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the TK-10 Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SR |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SR Leukemia cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SW-620 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SW-620 Colon cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| KM12 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the KM12 Colon cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NCI-H522 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H522 Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| M14 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the M14 Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| RPMI-8226 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the RPMI-8226 Leukemia cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NCI-H322M |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H322M Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| OVCAR-4 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the OVCAR-4 Ovarian cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| LOX IMVI |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the LOX IMVI Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| BT-549 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the BT-549 Breast cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SK-MEL-2 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-2 Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| A549 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the A549/ATCC Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SNB-75 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SNB-75 Central Nervous System cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| HCT-15 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HCT-15 Colon cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| HCT-116 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Colon cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SF-268 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-268 Central Nervous System cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| EKVX |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the EKVX Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| PC-3 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the PC-3 Prostate cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| T47D |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the T-47D Breast cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SK-OV-3 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-OV-3 Ovarian cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NCI-H460 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H460 Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| UACC-62 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UACC-62 Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| MDA-MB-435 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Breast cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| CAKI-1 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the CAKI-1 Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SF-295 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-295 Central Nervous System cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| IGROV-1 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Ovarian cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Hs-578T |
GI50 |
|
79.98 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HS 578T Breast cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| UACC-257 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UACC-257 Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| 786-0 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the 786-0 Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NCI-H226 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H226 Non-Small Cell Lung cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| HT-29 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HT29 Colon cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| SK-MEL-28 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-28 Melanoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| RXF 393 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the RXF 393 Renal cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| COLO 205 |
GI50 |
|
100000.0 |
nM |
PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the COLO 205 Colon cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Geminin |
Potency |
|
5804.8 |
nM |
PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Geminin |
Potency |
|
730.8 |
nM |
PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Tyrosyl-DNA phosphodiesterase 1 |
Potency |
|
29092.9 |
nM |
PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Escherichia coli |
Inhibition |
= |
5.58 |
% |
Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CAMBH media using NBS plates, by Resazurin F(560/590) |
CHEMBL4296182 |
| Pseudomonas aeruginosa |
Inhibition |
= |
4.31 |
% |
Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC in CAMBH media using NBS plates, by OD(600) |
CHEMBL4296182 |
| Candida albicans |
Inhibition |
= |
-0.11 |
% |
Antifungal activity against Candida albicans ATCC 90028 (CO-ADD:FG_001); MIC in YNB media using NBS plates, by OD630 |
CHEMBL4296182 |
| Staphylococcus aureus subsp. aureus |
Inhibition |
= |
-5.5 |
% |
Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020); MIC in CAMBH media using NBS plates, by Resazurin F(560/590) |
CHEMBL4296182 |
| Acinetobacter baumannii |
Inhibition |
= |
-14.65 |
% |
Antibacterial activity against Acinetobacter baumannii ATCC 19606 (CO-ADD:GN_034); MIC in CAMBH media using NBS plates, by Resazurin F(560/590) |
CHEMBL4296182 |
| Klebsiella pneumoniae |
Inhibition |
= |
3.14 |
% |
Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); MIC in CAMBH media using NBS plates, by OD(600) |
CHEMBL4296182 |
| Filobasidiella neoformans |
Inhibition |
= |
-5.11 |
% |
Antifungal activity against Cryptococcus neoformans H99 ATCC 208821 (CO-ADD:FG_002); MIC in YNB media using NBS plates, by Resazurin OD(600-570) |
CHEMBL4296182 |
