| ATP-dependent DNA helicase Q1 |
Potency |
= |
28183.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] |
CHEMBL1201862 |
| Aldehyde dehydrogenase 1A1 |
Potency |
= |
25118.9 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] |
CHEMBL1201862 |
| Thioredoxin glutathione reductase |
Potency |
= |
4466.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] |
CHEMBL1201862 |
| Unchecked |
Potency |
= |
35481.3 |
nM |
PUBCHEM_BIOASSAY: Quantitative High-Throughput Screen for Regulators of Epigenetic Control. (Class of assay: confirmatory) [Related pubchem assays: 1041, 1039, 890, 1036, 1653, 1035, 1043, 1038, 990, 597, 1042, 1037 ] |
CHEMBL1201862 |
| DNA polymerase beta |
Potency |
= |
22387.2 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Histone acetyltransferase GCN5 |
Potency |
|
39810.7 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] |
CHEMBL1201862 |
| Unchecked |
Potency |
|
35481.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485345, AID485355] |
CHEMBL1201862 |
| Vitamin D receptor |
Potency |
|
25118.9 |
nM |
PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] |
CHEMBL1201862 |
| Importin subunit beta-1/Snurportin-1 |
Potency |
|
89125.1 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] |
CHEMBL1201862 |
| ATP-dependent DNA helicase Q1 |
Potency |
|
50118.7 |
nM |
PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) - Round 2 Cherry Picks. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2367, AID593, AID594] |
CHEMBL1201862 |
| Thioredoxin reductase 1, cytoplasmic |
Potency |
|
56234.1 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] |
CHEMBL1201862 |
| DNA polymerase iota |
Potency |
|
15848.9 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] |
CHEMBL1201862 |
| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
IC50 |
= |
5741.0 |
nM |
PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493091, AID493120] |
CHEMBL1201862 |
| DNA polymerase eta |
Potency |
|
28183.8 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] |
CHEMBL1201862 |
| DNA polymerase kappa |
Potency |
|
70794.6 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] |
CHEMBL1201862 |
| Geminin |
Potency |
|
29092.9 |
nM |
PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Glutaminase kidney isoform, mitochondrial |
Potency |
|
31622.8 |
nM |
PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) |
CHEMBL1201862 |
| DNA dC->dU-editing enzyme APOBEC-3G |
Potency |
|
22387.2 |
nM |
PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Geminin |
Potency |
|
29092.9 |
nM |
PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Ataxin-2 |
Potency |
|
39810.7 |
nM |
PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Glucagon-like peptide 1 receptor |
Potency |
|
22387.2 |
nM |
PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Guanine nucleotide-binding protein G(s), subunit alpha |
Potency |
|
8912.5 |
nM |
PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Potency |
|
14125.4 |
nM |
PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Nuclear factor erythroid 2-related factor 2 |
Potency |
|
2818.4 |
nM |
PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
29092.9 |
nM |
PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Tyrosyl-DNA phosphodiesterase 1 |
Potency |
|
29092.9 |
nM |
PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Tyrosyl-DNA phosphodiesterase 1 |
Potency |
|
20596.2 |
nM |
PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Isocitrate dehydrogenase [NADP] cytoplasmic |
Potency |
|
29092.9 |
nM |
PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Rap guanine nucleotide exchange factor 3 |
Potency |
|
25118.9 |
nM |
PubChem BioAssay. qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Serine/threonine-protein kinase PLK1 |
Potency |
|
37685.8 |
nM |
PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Rap guanine nucleotide exchange factor 3 |
Potency |
|
44668.4 |
nM |
PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
