| Prelamin-A/C |
Potency |
= |
50.1 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
EC50 |
= |
14257.0 |
nM |
PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Inhibitors of Luciferase Translation or Activity in H4 Neuroglioblastoma Cells. (Class of assay: confirmatory) [Related pubchem assays: 1813 (Primary HTS), 1827 (Project Summary)] |
CHEMBL1201862 |
| Survival motor neuron protein |
Potency |
= |
25118.9 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
CC50 |
= |
5980.0 |
nM |
PUBCHEM_BIOASSAY: An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV). (Class of assay: confirmatory) [Related pubchem assays: 2391 ] |
CHEMBL1201862 |
| Unchecked |
IC50 |
= |
1910.0 |
nM |
PUBCHEM_BIOASSAY: A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
EC50 |
> |
120000.0 |
nM |
PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS to Identify Inhibitors of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation in H4 Neuroglioblastoma Cells. (Class of assay: confirmatory) [Related pubchem assays: 1827 (Project Summary), 1813 (Primary HTS)] |
CHEMBL1201862 |
| Unchecked |
EC50 |
= |
14703.0 |
nM |
PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells. (Class of assay: confirmatory) [Related pubchem assays: 1827 (Project Summary), 1813 (Primary HTS)] |
CHEMBL1201862 |
| DNA polymerase beta |
Potency |
= |
100000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Nuclear factor erythroid 2-related factor 2 |
Potency |
|
461.1 |
nM |
PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] |
CHEMBL1201862 |
| ATPase family AAA domain-containing protein 5 |
Potency |
|
16353.5 |
nM |
PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] |
CHEMBL1201862 |
| DNA polymerase iota |
Potency |
|
89125.1 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] |
CHEMBL1201862 |
| Vero |
IC50 |
|
11770.0 |
nM |
PUBCHEM_BIOASSAY: A Cell-Based Confirmatory Screen for Compounds that Inhibit VEEV, TC-83. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588723] |
CHEMBL1201862 |
| HEK293 |
Potency |
|
10000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] |
CHEMBL1201862 |
| Unchecked |
Potency |
|
1000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS for inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249, AID540278] |
CHEMBL1201862 |
| Glycoprotein hormones alpha chain |
Potency |
|
501.2 |
nM |
PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) |
CHEMBL1201862 |
| No relevant target |
IC50 |
> |
67547.0 |
nM |
PubChem BioAssay. Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Nuclear receptor subfamily 0 group B member 1 |
IC50 |
> |
22516.0 |
nM |
PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
28183.8 |
nM |
PubChem BioAssay. qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Candida albicans |
MIC |
> |
20000.0 |
nM |
Antifungal activity against Candida albicans ATCC 90028 (CO-ADD:FG_001); MIC in YNB media using NBS plates, by OD630 |
CHEMBL4513161 |
| Filobasidiella neoformans |
MIC |
> |
20000.0 |
nM |
Antifungal activity against Cryptococcus neoformans H99 ATCC 208821 (CO-ADD:FG_002); MIC in YNB media using NBS plates, by Resazurin OD(600-570) |
CHEMBL4513161 |
| Escherichia coli |
MIC |
> |
20000.0 |
nM |
Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CAMBH media using NBS plates, by OD(600) |
CHEMBL4513161 |
| Klebsiella pneumoniae |
MIC |
> |
20000.0 |
nM |
Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); MIC in CAMBH media using NBS plates, by OD(600) |
CHEMBL4513161 |
| Pseudomonas aeruginosa |
MIC |
> |
20000.0 |
nM |
Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC in CAMBH media using NBS plates, by OD(600) |
CHEMBL4513161 |
| Acinetobacter baumannii |
MIC |
> |
20000.0 |
nM |
Antibacterial activity against Acinetobacter baumannii ATCC 19606 (CO-ADD:GN_034); MIC in CAMBH media using NBS plates, by OD600 |
CHEMBL4513161 |
| Pseudomonas aeruginosa |
MIC |
> |
20000.0 |
nM |
Antibacterial activity against Pseudomonas aeruginosa PAO397 [PAO1 d(mexAB-oprM) d(mexCD-oprJ) d(mexEF-oprN) d(mexJKL) d(mexXY) d(opmH)] (CO-ADD:GN_211); MIC in CAMBH media using NBS plates, by OD(600) |
CHEMBL4513161 |
| Staphylococcus aureus subsp. aureus |
MIC |
> |
20000.0 |
nM |
Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020); MIC in CAMBH media, using NBS plates, by OD(600) |
CHEMBL4513161 |
| Erythrocyte |
HC10 |
> |
20.0 |
uM |
Haemolysis of human Red Blood Cells (CO-ADD:HA_150); HC10, by OD(450) |
CHEMBL4513161 |
| HEK293 |
CC50 |
> |
20000.0 |
nM |
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590) |
CHEMBL4513161 |
