| ATP-dependent DNA helicase Q1 |
Potency |
= |
12589.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] |
CHEMBL1201862 |
| Endoplasmic reticulum-associated amyloid beta-peptide-binding protein |
Potency |
= |
31622.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Lysine-specific demethylase 4D-like |
Potency |
= |
17782.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
IC50 |
= |
4790.0 |
nM |
PUBCHEM_BIOASSAY: A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag - Counter Screen. (Class of assay: confirmatory) [Related pubchem assays: 1903, 1909, 2102 ] |
CHEMBL1201862 |
| Tyrosyl-DNA phosphodiesterase 1 |
Potency |
= |
4466.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Microtubule-associated protein tau |
Potency |
= |
28183.8 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] |
CHEMBL1201862 |
| Aldehyde dehydrogenase 1A1 |
Potency |
= |
35481.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] |
CHEMBL1201862 |
| Thioredoxin glutathione reductase |
Potency |
= |
44668.4 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] |
CHEMBL1201862 |
| 4'-phosphopantetheinyl transferase ffp |
Potency |
= |
14125.4 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Arachidonate 15-lipoxygenase |
Potency |
= |
19952.6 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Microtubule-associated protein tau |
Potency |
= |
39810.7 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] |
CHEMBL1201862 |
| Putative fructose-1,6-bisphosphate aldolase |
Potency |
= |
5000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] |
CHEMBL1201862 |
| Beta-lactamase AmpC |
Potency |
= |
28183.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] |
CHEMBL1201862 |
| Endoplasmic reticulum-associated amyloid beta-peptide-binding protein |
Potency |
= |
10000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Lysosomal alpha-glucosidase |
Potency |
= |
17782.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] |
CHEMBL1201862 |
| DNA polymerase beta |
Potency |
= |
44668.4 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Lysine-specific demethylase 4A |
Potency |
|
1584.9 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] |
CHEMBL1201862 |
| 6-phospho-1-fructokinase |
Potency |
|
33807.8 |
nM |
PUBCHEM_BIOASSAY: Inhibitors of T. brucei phosphofructokinase: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768] |
CHEMBL1201862 |
| 6-phospho-1-fructokinase |
Potency |
|
26854.5 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768, AID492961] |
CHEMBL1201862 |
| Large T antigen |
IC50 |
|
7740.0 |
nM |
PUBCHEM_BIOASSAY: Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1909, AID2102, AID2501, AID2615, AID2775, AID449729, AID485276, AID485288] |
CHEMBL1201862 |
| Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 |
Potency |
|
8912.5 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] |
CHEMBL1201862 |
| 6-phospho-1-fructokinase |
Potency |
|
23934.1 |
nM |
PUBCHEM_BIOASSAY: Tb PFK orthogonal confirmatory assay using ATP depletion (Kinase-Glo Plus) as an alternative measure of Tb PFK activity: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768] |
CHEMBL1201862 |
| Plasmodium falciparum |
Potency |
|
4653.5 |
nM |
PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] |
CHEMBL1201862 |
| DNA polymerase iota |
Potency |
|
28183.8 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] |
CHEMBL1201862 |
| Plasmodium falciparum |
Potency |
|
18526.0 |
nM |
PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] |
CHEMBL1201862 |
| Glutaminase kidney isoform, mitochondrial |
Potency |
|
22387.2 |
nM |
PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Geminin |
Potency |
|
29092.9 |
nM |
PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Potency |
|
95283.4 |
nM |
PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Serine/threonine-protein kinase PLK1 |
Potency |
|
26679.5 |
nM |
PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
| DNA-(apurinic or apyrimidinic site) lyase |
Potency |
|
1584.9 |
nM |
PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Human immunodeficiency virus type 1 Tat protein |
IC50 |
|
68534.0 |
nM |
PubChem BioAssay. An HIV-1 Tat-TAR Fluorescence Polarization (FP) Counter Screen to evaluate Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
IC50 |
|
16390.0 |
nM |
PubChem BioAssay. High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G:#A time-resolved fluorescence resonance energy transfer (TR-FRET) assay for HIV-1 Vif-APOBEC3G interaction. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NON-PROTEIN TARGET |
CC50 |
> |
40000.0 |
nM |
PubChem BioAssay. A cell based assay for assessing vero cell cytotoxicity of Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G. (Class of assay: confirmatory) |
CHEMBL1201862 |
