| Endoplasmic reticulum-associated amyloid beta-peptide-binding protein |
Potency |
= |
39810.7 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Histone-lysine N-methyltransferase MLL |
Potency |
= |
12589.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] |
CHEMBL1201862 |
| Microtubule-associated protein tau |
Potency |
= |
15848.9 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] |
CHEMBL1201862 |
| Thioredoxin glutathione reductase |
Potency |
= |
1000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] |
CHEMBL1201862 |
| MAP kinase ERK2 |
Potency |
= |
50118.7 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Menin/Histone-lysine N-methyltransferase MLL |
Potency |
= |
17782.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Beta-lactamase AmpC |
Potency |
= |
631.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] |
CHEMBL1201862 |
| Endoplasmic reticulum-associated amyloid beta-peptide-binding protein |
Potency |
= |
12589.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Lysine-specific demethylase 4A |
Potency |
|
79432.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] |
CHEMBL1201862 |
| Bromodomain adjacent to zinc finger domain protein 2B |
Potency |
|
79432.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] |
CHEMBL1201862 |
| Vitamin D receptor |
Potency |
|
89125.1 |
nM |
PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] |
CHEMBL1201862 |
| Plasmodium falciparum |
Potency |
|
18526.0 |
nM |
PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] |
CHEMBL1201862 |
| Thioredoxin reductase 1, cytoplasmic |
Potency |
|
2511.9 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] |
CHEMBL1201862 |
| DNA polymerase iota |
Potency |
|
17782.8 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] |
CHEMBL1201862 |
| Dengue virus type 2 NS3 protein |
IC50 |
|
69740.0 |
nM |
PUBCHEM_BIOASSAY: Primary and Confirmatory Screening for Flavivirus Genomic Capping Enzyme Inhibition. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588708, AID588742] |
CHEMBL1201862 |
| Unchecked |
Potency |
|
25217.2 |
nM |
PubChem BioAssay. qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Fluorescein FP. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
96802.3 |
nM |
PubChem BioAssay. qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: HTRF Assay. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Werner syndrome ATP-dependent helicase |
Potency |
|
35481.3 |
nM |
PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
112641.3 |
nM |
PubChem BioAssay. qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Texas Red FP. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Tyrosyl-DNA phosphodiesterase 1 |
Potency |
|
5173.5 |
nM |
PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Parathyroid hormone receptor |
Potency |
|
3981.1 |
nM |
PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Serine/threonine-protein kinase PLK1 |
Potency |
|
26679.5 |
nM |
PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
