| Unchecked |
Potency |
|
37221.2 |
nM |
PubChem BioAssay. Cell Proliferation Assay against the TMD8 Cell Line (Caspase readout at 16 hrs). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
29824.5 |
nM |
PubChem BioAssay. qHTS Assay for Identification of Small Molecule Antagonists for NFkB Signaling Pathway. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
26.4 |
nM |
PubChem BioAssay. Cell Proliferation Assay against a hMSC Cell Line. (Class of assay: confirmatory) |
CHEMBL1201862 |
| NON-PROTEIN TARGET |
Potency |
|
18654.8 |
nM |
PubChem BioAssay. Cytotoxicity counterscreen for NFkB agonists and antagonists. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
33173.4 |
nM |
PubChem BioAssay. Cell Proliferation Assay against the TMD8 Cell Line (Caspase readout at 8 hrs). (Class of assay: confirmatory) |
CHEMBL1201862 |
| MDA-MB-231 |
Activity |
|
|
|
Induction of morphological changes in red fluorescent labelled human MDA-MB-231 cells assessed as rounded-up cells at 6.25 to 1000 nM after 16 hrs by microscopic analysis |
CHEMBL3132762 |
| MDA-MB-231 |
GI50 |
= |
25.0 |
nM |
Growth inhibition of human MDA-MB-231 cells after 3 days by DAPI staining |
CHEMBL3132762 |
| Dual specificity mitogen-activated protein kinase kinase 2 |
IC50 |
= |
1.6 |
nM |
Inhibition of B-Raf activated MEK2 (unknown origin) assessed as ERK2-mediated MBP phosphorylation after 30 mins by ELISA |
CHEMBL3132762 |
| Dual specificity mitogen-activated protein kinase kinase 1 |
IC50 |
= |
3.4 |
nM |
Inhibition of B-Raf activated MEK1 (unknown origin) assessed as ERK2-mediated MBP phosphorylation after 30 mins by ELISA |
CHEMBL3132762 |
| Unchecked |
Potency |
|
935.0 |
nM |
PubChem BioAssay. qHTS Assay for Identifying Gametocytocidal Compounds. (Class of assay: confirmatory) |
CHEMBL1201862 |
| ADMET |
PPB |
|
99.05 |
% |
ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole human plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound. |
CHEMBL3301361 |
| Unchecked |
Potency |
|
23485.0 |
nM |
PubChem BioAssay. Immunotoxin (HA22) sensitization/mitigation study - treatment arm (low dose). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
16626.1 |
nM |
PubChem BioAssay. Immunotoxin (SS1P) sensitization/mitigation study - treatment arm. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
29565.9 |
nM |
PubChem BioAssay. Immunotoxin (SS1P) sensitization/mitigation study. Vehicle arm (DMEM). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
29565.9 |
nM |
PubChem BioAssay. Immunotoxin (HA22) sensitization/mitigation study. Vehicle arm (PBS). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Homo sapiens |
T1/2 |
> |
40.0 |
hr |
Effective half life in patient |
CHEMBL3616393 |
| Rattus norvegicus |
T1/2 |
> |
30.0 |
hr |
Plasma half life in po dosed Sprague-Dawley rat |
CHEMBL3616393 |
| NON-PROTEIN TARGET |
IC50 |
= |
96.0 |
nM |
Growth inhibition of human MDA-MB-175-VII cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
> |
1000.0 |
nM |
Growth inhibition of human EFM19 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
18.0 |
nM |
Growth inhibition of human RKO cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
55.0 |
nM |
Growth inhibition of human HCT8 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
23.0 |
nM |
Growth inhibition of human NCI-H508 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
632.0 |
nM |
Growth inhibition of human DLD1 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
61.0 |
nM |
Growth inhibition of human T84 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
23.0 |
nM |
Growth inhibition of human KM12 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
74.0 |
nM |
Growth inhibition of human SW837 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
5.0 |
nM |
Growth inhibition of human LS1034 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
1.0 |
nM |
Growth inhibition of human COLO205 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
4.0 |
nM |
Growth inhibition of human SW1463 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
2.0 |
nM |
Growth inhibition of human HT-29 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
37.0 |
nM |
Growth inhibition of human SW480 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
3.0 |
nM |
Growth inhibition of human SW1417 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
329.0 |
nM |
Growth inhibition of human COR-L23 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
34.0 |
nM |
Growth inhibition of human A549 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
52.0 |
nM |
Growth inhibition of human NCI-H1355 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
53.0 |
nM |
Growth inhibition of human NCI-H1792 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
29.0 |
nM |
Growth inhibition of human NCI-H23 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
4.0 |
nM |
Growth inhibition of human Calu6 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
2.0 |
nM |
Growth inhibition of human MV522 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
> |
1000.0 |
nM |
Growth inhibition of human NCI-H1155 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
> |
1000.0 |
nM |
Growth inhibition of human SW1573 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
> |
1000.0 |
nM |
Growth inhibition of human HOP62 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
127.0 |
nM |
Growth inhibition of human SW900 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
22.0 |
nM |
Growth inhibition of human A427 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
> |
1000.0 |
nM |
Growth inhibition of human HCC827 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
158.0 |
nM |
Growth inhibition of human Calu3 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
2.0 |
nM |
Growth inhibition of human NCI-H727 cells incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
16.0 |
nM |
Growth inhibition of human MDA-MB-175-VII cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
30.0 |
nM |
Growth inhibition of human EFM19 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
5.0 |
nM |
Growth inhibition of human RKO cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
14.0 |
nM |
Growth inhibition of human HCT8 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
8.0 |
nM |
Growth inhibition of human NCI-H508 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
93.0 |
nM |
Growth inhibition of human DLD1 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
30.0 |
nM |
Growth inhibition of human T84 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
10.0 |
nM |
Growth inhibition of human KM12 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
25.0 |
nM |
Growth inhibition of human SW837 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
4.0 |
nM |
Growth inhibition of human LS1034 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
1.0 |
nM |
Growth inhibition of human COLO205 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
4.0 |
nM |
Growth inhibition of human SW1463 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
1.0 |
nM |
Growth inhibition of human HT-29 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
26.0 |
nM |
Growth inhibition of human SW480 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
3.0 |
nM |
Growth inhibition of human SW1417 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
37.0 |
nM |
Growth inhibition of human COR-L23 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
16.0 |
nM |
Growth inhibition of human A549 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
27.0 |
nM |
Growth inhibition of human NCI-H1355 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
35.0 |
nM |
Growth inhibition of human NCI-H1792 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
20.0 |
nM |
Growth inhibition of human NCI-H23 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
3.0 |
nM |
Growth inhibition of human Calu6 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
1.0 |
nM |
Growth inhibition of human MV522 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
10.0 |
nM |
Growth inhibition of human NCI-H1155 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
38.0 |
nM |
Growth inhibition of human SW1573 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
50.0 |
nM |
Growth inhibition of human HOP62 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
72.0 |
nM |
Growth inhibition of human SW900 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
10.0 |
nM |
Growth inhibition of human A427 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
40.0 |
nM |
Growth inhibition of human HCC827 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
39.0 |
nM |
Growth inhibition of human Calu3 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
IC50 |
= |
2.0 |
nM |
Growth inhibition of human NCI-H727 cells at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.39 |
|
Growth inhibition of human MDA-MB-175-VII cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human EFM19 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.34 |
|
Growth inhibition of human RKO cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.39 |
|
Growth inhibition of human HCT8 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.58 |
|
Growth inhibition of human NCI-H508 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human DLD1 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human T84 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.6 |
|
Growth inhibition of human KM12 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human SW837 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.84 |
|
Growth inhibition of human LS1034 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.88 |
|
Growth inhibition of human COLO205 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.94 |
|
Growth inhibition of human SW1463 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.95 |
|
Growth inhibition of human HT-29 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human SW480 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human SW1417 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.17 |
|
Growth inhibition of human COR-L23 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.52 |
|
Growth inhibition of human A549 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.57 |
|
Growth inhibition of human NCI-H1355 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.73 |
|
Growth inhibition of human NCI-H1792 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.76 |
|
Growth inhibition of human NCI-H23 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.79 |
|
Growth inhibition of human Calu6 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
0.8 |
|
Growth inhibition of human MV522 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human NCI-H1155 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human SW1573 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human HOP62 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human SW900 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human A427 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human HCC827 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
|
|
|
Growth inhibition of human Calu3 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| NON-PROTEIN TARGET |
CI |
= |
1.09 |
|
Growth inhibition of human NCI-H727 cells assessed combination index at 1:10 molar ratio of compound in presence of N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecar- boxamide incubated for 72 hrs by Cell-titer-Glo reagent based assay |
CHEMBL3880386 |
| Adaptor-associated kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase ABL |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase ABL2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Acyl-CoA dehydrogenase family member 10 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Acyl-CoA dehydrogenase family member 11 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Peroxisomal acyl-coenzyme A oxidase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Peroxisomal acyl-coenzyme A oxidase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Actin-related protein 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Actin-related protein 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Activin receptor type-1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Activin receptor type-1B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Activin receptor type-2B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase receptor R3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Uncharacterized aarF domain-containing protein kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Chaperone activity of bc1 complex-like, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Uncharacterized aarF domain-containing protein kinase 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Adenosine kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| G-protein coupled receptor kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Adenylate kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase AKT |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase AKT2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase AKT3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Adenine phosphoribosyltransferase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase A-Raf |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase Aurora-A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase Aurora-B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Breakpoint cluster region protein |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| BMP-2-inducible protein kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Bone morphogenetic protein receptor type-1A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Bone morphogenetic protein receptor type-1B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Bone morphogenetic protein receptor type-2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase B-raf |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase BTK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| CaM kinase II delta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| CaM kinase II gamma |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| CaM kinase IV |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| CaM-kinase kinase beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cysteine--tRNA ligase, cytoplasmic |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase MRCK-A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase MRCK beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase MRCK gamma |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cell division cycle 7-related protein kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 10 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 12 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 13 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PCTAIRE-1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PCTAIRE-2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PCTAIRE-3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 7 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase 9 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cyclin-dependent kinase-like 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Chromodomain-helicase-DNA-binding protein 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase Chk1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Citron Rho-interacting kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificty protein kinase CLK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity protein kinase CLK2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity protein kinase CLK3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity protein kinase CLK4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| UMP-CMP kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase CSK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Casein kinase I alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Casein kinase I delta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Casein kinase I epsilon |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Casein kinase I gamma 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Casein kinase I gamma 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Casein kinase I isoform gamma-3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Unchecked |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Casein kinase II alpha (prime) |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Cytochrome c1, heme protein, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Deoxycytidine kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| dCTP pyrophosphatase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Epithelial discoidin domain-containing receptor 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Discoidin domain-containing receptor 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| ATP-dependent RNA helicase DDX1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| ATP-dependent RNA helicase DDX3X |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| ATP-dependent RNA helicase DDX42 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Probable ATP-dependent RNA helicase DDX6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Delta(24)-sterol reductase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| ATP-dependent RNA helicase DHX30 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| DnaJ homolog subfamily A member 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual-specificity tyrosine-phosphorylation regulated kinase 1A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Epidermal growth factor receptor erbB1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Unchecked |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Eukaryotic translation initiation factor 5B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-A receptor 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-A receptor 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-A receptor 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-A receptor 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-A receptor 7 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-B receptor 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-B receptor 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-B receptor 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ephrin type-B receptor 6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| General transcription and DNA repair factor IIH helicase subunit XPD |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Electron transfer flavoprotein subunit beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Phenylalanine--tRNA ligase beta subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ferrochelatase, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase FER |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase FES |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Fibroblast growth factor receptor 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase FGR |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase receptor FLT3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase FRK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase FYN |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase GAK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Glycine--tRNA ligase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| G protein-coupled receptor kinase 6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Glycogen synthase kinase-3 alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Glycogen synthase kinase-3 beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Eukaryotic peptide chain release factor GTP-binding subunit ERF3B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Nucleolar GTP-binding protein 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase HCK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Heme oxygenase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Putative heat shock protein HSP 90-beta 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Isoleucine--tRNA ligase, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase ICK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Insulin-like growth factor I receptor |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Inhibitor of nuclear factor kappa B kinase epsilon subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase ILK-1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Inosine-5'-monophosphate dehydrogenase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Insulin receptor |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Interleukin-1 receptor-associated kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Interleukin-1 receptor-associated kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Interleukin-1 receptor-associated kinase 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase JAK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase JAK2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase LATS1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase LCK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| LIM domain kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| LIM domain kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase Lyn |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity mitogen-activated protein kinase kinase 1 |
Kd |
= |
62.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity mitogen-activated protein kinase kinase 2 |
Kd |
= |
9.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity mitogen-activated protein kinase kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity mitogen-activated protein kinase kinase 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity mitogen-activated protein kinase kinase 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity mitogen-activated protein kinase kinase 6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase 11 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase 6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase kinase 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase kinase kinase kinase 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP kinase ERK2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| c-Jun N-terminal kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP kinase p38 beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP kinase p38 alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase 15 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP kinase ERK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mitogen-activated protein kinase 7 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| c-Jun N-terminal kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| c-Jun N-terminal kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP kinase-activated protein kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP kinase-activated protein kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP kinase-activated protein kinase 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP/microtubule affinity-regulating kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase c-TAK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| MAP/microtubule affinity-regulating kinase 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| S-adenosylmethionine synthase isoform type-2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| DNA replication licensing factor MCM4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Midasin |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Maternal embryonic leucine zipper kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Hepatocyte growth factor receptor |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Misshapen-like kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Macrophage-stimulating protein receptor |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Myosin-10 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Myosin-14 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Myosin light chain kinase, smooth muscle |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Myosin light chain kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| RNA cytidine acetyltransferase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase Nek1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase NEK2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase Nek3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase NEK9 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine protein kinase NLK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Quinone reductase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Nerve growth factor receptor Trk-A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| NUAK family SNF1-like kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Obg-like ATPase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dynamin-like 120 kDa protein, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Multifunctional protein ADE2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PAK 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PAK 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PAK6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| PAS domain-containing serine/threonine-protein kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Choline-phosphate cytidylyltransferase A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Platelet-derived growth factor receptor beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Unchecked |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Pyridoxal kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Phosphatidylethanolamine-binding protein 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Phosphofructokinase platelet type |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Membrane-associated progesterone receptor component 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Phosphorylase kinase gamma subunit 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PIM1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PIM2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine- and threonine-specific cdc2-inhibitory kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase N1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase N2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase N3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PLK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase PLK4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| AMP-activated protein kinase, alpha-1 subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| cAMP-dependent protein kinase alpha-catalytic subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| cAMP-dependent protein kinase beta-1 catalytic subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| cAMP-dependent protein kinase, gamma catalytic subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| AMP-activated protein kinase, gamma-1 subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| AMP-activated protein kinase, gamma-2 subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase C alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase C beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase C delta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Unchecked |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase C iota |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase C theta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase C zeta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase D2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein kinase C nu |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| cGMP-dependent protein kinase 1 beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Unchecked |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| 26S protease regulatory subunit 6B |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Focal adhesion kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Protein tyrosine kinase 2 beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase BRK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Brain glycogen phosphorylase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Liver glycogen phosphorylase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Uncharacterized protein FLJ45252 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ras-related protein Rab-10 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ras-related protein Rab-27A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ras-related protein Rab-6A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Rab-like protein 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| GTP-binding nuclear protein Ran |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase receptor RET |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase RIPK2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Receptor-interacting serine/threonine-protein kinase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Rho-associated protein kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Rho-associated protein kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ribosomal protein S6 kinase alpha 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ribosomal protein S6 kinase alpha 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ribosomal protein S6 kinase alpha 4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ribosomal protein S6 kinase alpha 5 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ribosomal protein S6 kinase alpha 6 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Ribosomal protein S6 kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Septin-9 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase SIK2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase SIK3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Exosome RNA helicase MTR4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| ADP/ATP translocase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| ADP/ATP translocase 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Structural maintenance of chromosomes protein 1A |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Structural maintenance of chromosomes protein 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase SRC |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Signal recognition particle receptor subunit alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase 10 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase 11 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase 16 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase 24 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase MST4 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase MST2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase MST1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| STE20-related kinase adapter protein alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase SYK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase TAO1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase TAO2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase TAO3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase TBK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase TEC |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity testis-specific protein kinase 1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity testis-specific protein kinase 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| TGF-beta receptor type I |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| TGF-beta receptor type II |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Thyroid hormone receptor-associated protein 3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| TRAF2- and NCK-interacting kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Non-receptor tyrosine-protein kinase TNK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine kinase non-receptor protein 2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| DNA topoisomerase II alpha |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| DNA topoisomerase II beta |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| TP53-regulating kinase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Dual specificity protein kinase TTK |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Elongation factor Tu, mitochondrial |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase TYK2 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase ULK1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase ULK3 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Serine/threonine-protein kinase WEE1 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosyl-tRNA synthetase |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Tyrosine-protein kinase YES |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| Mixed lineage kinase 7 |
Kd |
> |
30000.0 |
nM |
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. |
CHEMBL3991601 |
| SARS-CoV-2 |
Inhibition |
= |
76.63 |
% |
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging |
CHEMBL4303101 |
| SARS-CoV-2 |
Hit score |
= |
-0.4857 |
|
Antiviral activity against SARS-CoV-2 (USA-WA1/2020 strain) measured by imaging in HRCE cells at MOI 0.4 after 96 hrs (reported as hit score from 0-1 for on-disease vs off-disease activity: scores >0.6 considered hits) |
CHEMBL4303122 |
| A-375 |
IC50 |
= |
0.74 |
nM |
Antiproliferative activity against human A375 cells assessed as reduction in cell viability |
CHEMBL4376845 |
| Mitogen-activated protein kinase; ERK1/ERK2 |
Inhibition |
|
|
% |
Inhibition of ERK1/2 phosphorylation in human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at assessed as increase in MEK1/2 phosphorylation at Ser 217/221 residues at 25 nM incubated for 2 to 8 hrs by Western blotting analysis |
CHEMBL4420081 |
| MIA PaCa-2 |
Inhibition |
|
|
% |
Antitumor activity against human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at xenografted in BomTacNMRI-Foxn1 nu mouse assessed as inhibition of tumor regression at 0.125 mg/kg, po BID relative to control |
CHEMBL4420081 |
| MIA PaCa-2 |
TGI |
= |
50.0 |
% |
Antitumor activity against human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at xenografted in BomTacNMRI-Foxn1 nu mouse assessed as inhibition of tumor growth at 0.05 mg/kg, po BID relative to control |
CHEMBL4420081 |
| Mitogen-activated protein kinase; ERK1/ERK2 |
Inhibition |
= |
65.0 |
% |
Inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 residues in human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at 50 nM incubated for 2 to 8 hrs by Western blotting analysis relative to control |
CHEMBL4420081 |
| MIA PaCa-2 |
TGI |
= |
73.0 |
% |
Antitumor activity against human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at xenografted in BomTacNMRI-Foxn1 nu mouse assessed as inhibition of tumor growth at 0.125 mg/kg, po BID relative to control |
CHEMBL4420081 |
| MIA PaCa-2 |
Inhibition |
|
|
% |
Antitumor activity against human MIAPaCa2 cells grown under 3D anchorage-independent soft-agar conditions at xenografted in BomTacNMRI-Foxn1 nu mouse assessed as inhibition of tumor regression at 0.05 mg/kg, po BID relative to control |
CHEMBL4420081 |
| P-glycoprotein 1 |
EC50 |
= |
247.0 |
nM |
Inhibition of ABCB1 in human A2780/ADR cells assessed as potentiation of daunorubicin-induced cytotoxicity measured after 72 hrs by MTT assay |
CHEMBL4422621 |
| Dual specificity mitogen-activated protein kinase kinase 1 |
IC50 |
= |
0.7 |
nM |
Inhibition of MEK1 (unknown origin) |
CHEMBL4433204 |
| Dual specificity mitogen-activated protein kinase kinase 2 |
IC50 |
= |
14.9 |
nM |
Inhibition of MEK2 (unknown origin) |
CHEMBL4433204 |
| Replicase polyprotein 1ab |
Inhibition |
= |
19.64 |
% |
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate |
CHEMBL4495564 |
| Replicase polyprotein 1ab |
Inhibition |
= |
8.399 |
% |
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate |
CHEMBL4495564 |
| SARS-CoV-2 |
Inhibition |
= |
-0.19 |
% |
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging |
CHEMBL4495565 |
| SARS-CoV-2 |
Inhibition |
= |
-0.36 |
% |
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging |
CHEMBL4495565 |
| SARS-CoV-2 |
Inhibition |
= |
-0.36 |
% |
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging |
CHEMBL4495565 |
| SARS-CoV-2 |
Inhibition |
= |
-0.19 |
% |
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging |
CHEMBL4495565 |
| SARS-CoV-2 |
IC50 |
> |
20000.0 |
nM |
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging |
CHEMBL4651402 |
| SARS-CoV-2 |
IC50 |
< |
19952.62 |
nM |
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging |
CHEMBL4651402 |
| Unchecked |
IC50 |
= |
2.4 |
nM |
Antiproliferative activity against human A375 cells harboring BRAF V600E mutant assessed as inhibition of cell viability after 96 hrs by Celltiter-Glo assay |
CHEMBL4680253 |
| MDA-MB-231 |
IC50 |
= |
18.0 |
nM |
Antiproliferative activity against human MDA-MB-231 cells harboring KRAS G13D/BRAF G464V mutant assessed as inhibition of cell viability after 96 hrs by Celltiter-Glo assay |
CHEMBL4680253 |
| HCT-116 |
IC50 |
= |
19.0 |
nM |
Antiproliferative activity against human HCT116 cells harboring KRAS G13D mutant assessed as inhibition of cell viability after 96 hrs by Celltiter-Glo assay |
CHEMBL4680253 |
| A549 |
IC50 |
= |
460.0 |
nM |
Antiproliferative activity against human A549 cells harboring KRAS G12S mutant assessed as inhibition of cell viability after 96 hrs by Celltiter-Glo assay |
CHEMBL4680253 |
| HL-60 |
IC50 |
= |
3.0 |
nM |
Antiproliferative activity against human HL60 cells harboring NRAS K61L mutant assessed as inhibition of cell viability after 96 hrs by Celltiter-Glo assay |
CHEMBL4680253 |
| KYSE-520 cell line |
IC50 |
= |
10.0 |
nM |
Antiproliferative activity against human KYSE-520 cells |
CHEMBL4699491 |
| Dual specificity mitogen-activated protein kinase kinase; MEK1/2 |
IC50 |
< |
1.0 |
nM |
Inhibition of MEK in human KYSE-520 cells assessed as reduction in p-ERK levels |
CHEMBL4699491 |
| DLD-1 |
Activity |
|
|
|
Induction of apoptosis in human DLD-1 cells harboring KRAS G13D mutant assessed as cleaved-PRAP at 0.1 nM measured after 24 to 48 hrs |
CHEMBL5036304 |
| Dual specificity mitogen-activated protein kinase kinase 1 |
T1/2 |
= |
0.4167 |
hr |
Displacement of [32]P from human MEK1 (K97R) assessed as half time in presence of [gamma-33P]-ATP measured after 120 mins by microbeta scintillation counter |
CHEMBL5046286 |
| Unchecked |
Kd |
= |
3.0 |
nM |
Binding affinity to MEK1/2 (unknown origin) assessed as dissociation constant |
CHEMBL5120797 |
| Unchecked |
IC50 |
= |
2.0 |
nM |
Inhibition of MEK1/2 (unknown origin) |
CHEMBL5120797 |
| Dual specificity mitogen-activated protein kinase kinase 1 |
IC50 |
= |
0.92 |
nM |
Non competitive inhibition of MEK1 (unknown origin) |
CHEMBL5131375 |
| Dual specificity mitogen-activated protein kinase kinase 2 |
IC50 |
= |
1.8 |
nM |
Non competitive inhibition of MEK2 (unknown origin) |
CHEMBL5131375 |
| Influenza A virus |
EC50 |
= |
16.0 |
nM |
Antiviral activity against influenza A RB1/H1N1pdm09 virus |
CHEMBL5131375 |
| Dual specificity mitogen-activated protein kinase kinase 1 |
IC50 |
= |
0.92 |
nM |
Inhibition of MEK1 (unknown origin) |
CHEMBL5131375 |
| Dual specificity mitogen-activated protein kinase kinase 2 |
IC50 |
= |
1.8 |
nM |
Inhibition of MEK2 (unknown origin) |
CHEMBL5131375 |
| A549 |
CC50 |
> |
20000.0 |
nM |
Cytotoxicity against human A549 cells |
CHEMBL5131375 |
| MDCK-II |
CC50 |
> |
20000.0 |
nM |
Cytotoxicity against MDCK-II cells |
CHEMBL5131375 |
| Influenza A virus |
Activity |
|
|
|
In vivo antiviral activity against influenza A virus infected in mouse assessed as reduction of vRNPs at 3 mg/kg, po |
CHEMBL5131375 |
| Middle East respiratory syndrome-related coronavirus |
Activity |
> |
95.0 |
% |
Antiviral activity against MERS-CoV infected in human HUh-7 cells at 0.1 to 10 uM |
CHEMBL5131376 |
| Dual specificity mitogen-activated protein kinase kinase; MEK1/2 |
IC50 |
= |
2.0 |
nM |
Inhibition of MEK 1/2 (unknown origin) |
CHEMBL5131376 |
