| Lysine-specific demethylase 4D-like |
Potency |
= |
31622.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Microtubule-associated protein tau |
Potency |
= |
17782.8 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] |
CHEMBL1201862 |
| Hypoxia-inducible factor 1 alpha |
Potency |
= |
10000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Agonists for Hypoxia Response Element Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 915 ] |
CHEMBL1201862 |
| Aldehyde dehydrogenase 1A1 |
Potency |
= |
31622.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] |
CHEMBL1201862 |
| Thioredoxin glutathione reductase |
Potency |
= |
56234.1 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] |
CHEMBL1201862 |
| 4'-phosphopantetheinyl transferase ffp |
Potency |
= |
22387.2 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Ferritin light chain |
Potency |
= |
39810.7 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] |
CHEMBL1201862 |
| Hypoxia-inducible factor 1 alpha |
Potency |
= |
10000.0 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway. (Class of assay: confirmatory) [Related pubchem assays: 914 ] |
CHEMBL1201862 |
| 15-hydroxyprostaglandin dehydrogenase [NAD+] |
Potency |
= |
28183.8 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] |
CHEMBL1201862 |
| Alpha-galactosidase A |
Potency |
= |
35481.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate. (Class of assay: confirmatory) [Related pubchem assays: 1472, 1467 ] |
CHEMBL1201862 |
| Lysosomal alpha-glucosidase |
Potency |
= |
35481.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] |
CHEMBL1201862 |
| Lysosomal alpha-glucosidase |
Potency |
= |
35481.3 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] |
CHEMBL1201862 |
| Runt-related transcription factor 1/Core-binding factor subunit beta |
IC50 |
= |
38500.0 |
nM |
PUBCHEM_BIOASSAY: uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay. Inhibition of protein-protein interaction using fluorescence resonance energy transfer (FRET) assay Secondary Screen (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1438, AID1496, AID1502, AID1550, AID1560, AID1645] |
CHEMBL1201862 |
| Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 |
Potency |
|
39810.7 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] |
CHEMBL1201862 |
| Runt-related transcription factor 1/Core-binding factor subunit beta |
IC50 |
= |
45100.0 |
nM |
PUBCHEM_BIOASSAY: Identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a time resolved fluorescence resonance energy transfer (TR-FRET) assay. Counterscreen (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1434, AID1496, AID1502, AID1550, AID1560, AID1645] |
CHEMBL1201862 |
| Importin subunit beta-1/Snurportin-1 |
Potency |
|
89125.1 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] |
CHEMBL1201862 |
| GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 |
Potency |
|
5623.4 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] |
CHEMBL1201862 |
| Thioredoxin reductase 1, cytoplasmic |
Potency |
|
19952.6 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] |
CHEMBL1201862 |
| Chromobox protein homolog 1 |
Potency |
|
89125.1 |
nM |
PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] |
CHEMBL1201862 |
| DNA polymerase iota |
Potency |
|
15848.9 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] |
CHEMBL1201862 |
| DNA polymerase eta |
Potency |
|
25118.9 |
nM |
PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] |
CHEMBL1201862 |
| Dengue virus type 2 NS3 protein |
IC50 |
|
88670.0 |
nM |
PUBCHEM_BIOASSAY: Primary and Confirmatory Screening for Flavivirus Genomic Capping Enzyme Inhibition. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588708, AID588742] |
CHEMBL1201862 |
| Thioredoxin reductase 1, cytoplasmic |
Potency |
|
25118.9 |
nM |
PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] |
CHEMBL1201862 |
| Unchecked |
Potency |
|
12589.3 |
nM |
PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
| ATP-dependent Clp protease proteolytic subunit |
Potency |
|
35481.3 |
nM |
PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Alpha-galactosidase A |
Potency |
|
35481.3 |
nM |
PubChem BioAssay. qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Glutaminase kidney isoform, mitochondrial |
Potency |
|
14125.4 |
nM |
PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) |
CHEMBL1201862 |
| Guanine nucleotide-binding protein G(s), subunit alpha |
Potency |
|
1000.0 |
nM |
PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Potency |
|
47754.8 |
nM |
PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Putative uncharacterized protein |
Potency |
|
44668.4 |
nM |
PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha |
Potency |
|
8912.5 |
nM |
PubChem BioAssay. qHTS for Inhibitors of PI5P4K: Confirmation in Primary Assay. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
31622.8 |
nM |
PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Serine/threonine-protein kinase PLK1 |
Potency |
|
21192.3 |
nM |
PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) |
CHEMBL1201862 |
| Unchecked |
Potency |
|
28183.8 |
nM |
PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors: Orthogonal Assay for Cherry-picked Compounds. (Class of assay: confirmatory) |
CHEMBL1201862 |
