Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Type
|
Relation
|
Value
|
Unit
|
||||||||
NAs.000001 | 7 | all-match | Adenosine deaminase | ![]() |
Ki | = | 6.4 | nM | Tested for binding affinity against calf intestinal Adenosine Deaminase (ADA) | CHEMBL1127396 | |
NAs.001962 | 2 | all-match | Unchecked | ![]() |
Other | = | 2.8 | None | Activate a partially purified type II cAMP-dependent protein kinase from bovine brain | CHEMBL1121590 | |
NAs.001962 | 2 | all-match | Phosphodiesterase 4 | ![]() |
Other | < | 0.05 | None | Susceptibility to be hydrolysed by a partially purified cAMP phosphodiesterase from rabbit kidney | CHEMBL1121590 | |
NAs.001962 | 2 | all-match | Phosphodiesterase 4 | ![]() |
IC50 | = | 150000.0 | nM | Inhibition of cAMP phosphodiesterase preparation from rabbit lung at a substrate concentration of 0.14 uM | CHEMBL1121590 | |
NAs.001962 | 2 | all-match | Phosphodiesterase 4 | ![]() |
IC50 | = | 500000.0 | nM | Inhibition of cAMP phosphodiesterase preparation from bovine heart at a substrate concentration of 0.14 uM | CHEMBL1121590 |