| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.000011 | 2 | all-match | HT-29 |  |
IC50 | = | 8700.0 | nM | Antiproliferative activity against human HT-29 cells | CHEMBL3097995 | |
| NAs.000011 | 2 | all-match | HeLa | |
IC50 | = | 4500.0 | nM | Antiproliferative activity against human HeLa cells | CHEMBL3097995 | |
| NAs.000011 | 2 | all-match | K562 | |
IC50 | = | 1000.0 | nM | Antiproliferative activity against human K562 cells | CHEMBL3097995 | |
| NAs.000011 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 2 | |
Ki | = | 15.0 | nM | Inhibition of IMPDH2 (unknown origin) | CHEMBL3097995 | |
| NAs.000011 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 1 | |
Ki | = | 13.0 | nM | Inhibition of IMPDH1 (unknown origin) | CHEMBL3097995 | |
| NAs.001062 | 7 | all-match | Phosphodiesterase 3 |  |
IC50 | = | 101000.0 | nM | Inhibition of phosphodiesterase 3 at 1 uM cAMP | CHEMBL1130051 | |
| NAs.001062 | 7 | all-match | Phosphodiesterase 4 | |
IC50 | = | 1800.0 | nM | Inhibition of phosphodiesterase 4 at 1 uM cAMP | CHEMBL1130051 | |