| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.000021 | 8 | ribose-match | Adenosine A1 receptor |  |
Other | = | 23.0 | % | Displacement of [3H]R-PIA from human recombinant adenosine A1 receptor expressed in CHO cells at 10 uM after 60 mins by liquid scintillation counting | CHEMBL2062514 | |
| NAs.000021 | 8 | ribose-match | Adenosine A2a receptor | |
Other | = | 7.0 | % | Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting | CHEMBL2062514 | |
| NAs.000021 | 8 | ribose-match | Adenosine A3 receptor | |
Ki | = | 10.1 | nM | Displacement of [3H]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting | CHEMBL2062514 | |
| NAs.000021 | 8 | ribose-match | Adenosine A3 receptor | |
Other | = | 78.4 | % | Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM incubated for 30 mins prior to forskolin-stimulation measured after 15 mins by enzyme immunoassay relative to NECA | CHEMBL2062514 | |