Showing 1 to 17 of 17 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000028 2 all-match Adenosine A1 receptor NAs.000028 Ki = 620.0 nM Binding affinity for adenosine A1 receptor as inhibition of 3[H]-R-PIA binding in rat brain CHEMBL1130877
NAs.000028 2 all-match Adenosine A2a receptor NAs.000028 Ki > 10000.0 nM Binding affinity for adenosine A2a receptor as inhibition of 3[H]-CGS 21680 binding in rat striatum CHEMBL1130877
NAs.000028 2 all-match Adenosine A3 receptor NAs.000028 Ki = 31.0 nM Binding affinity for adenosine A3 receptor as inhibition of [125I]AB-MECA binding to human receptor expressed in HEK 293 cells CHEMBL1130877
NAs.000769 8 all-match Adenosine A3 receptor NAs.000769 Ki = 149.0 nM Displacement of radioligand from human adenosine A3 receptor expressed in CHO cells CHEMBL1145629
NAs.000769 8 all-match Adenosine A1 receptor NAs.000769 Ki = 265.0 nM Displacement of radioligand from human adenosine A1 receptor expressed in CHO cells CHEMBL1145629
NAs.000769 8 all-match Adenosine A2a receptor NAs.000769 Other = 2.0 % Displacement of radioligand from human A2A adenosine receptor expressed in HEK293 cells at 10 uM CHEMBL1145629
NAs.000769 8 all-match Adenosine A2a receptor NAs.000769 Other = 2.0 % Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarbox-amidoadenosine from mouse recombinant adenosine A2A receptor expressed in HEK293 at 100 uM CHEMBL1145629
NAs.000769 8 all-match Unchecked NAs.000769 Other = 1.3 None Selectivity for mouse adenosine A3 receptor over mouse adenosine A1 receptor CHEMBL1145629
NAs.000769 8 all-match Adenosine A3 receptor NAs.000769 Ki = 877.0 nM Displacement of [125I]N6-(-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A3 receptor expressed in HEK293 cells CHEMBL1145629
NAs.000769 8 all-match Adenosine A1 receptor NAs.000769 Ki = 1160.0 nM Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A1 receptor expressed in HEK293 cells CHEMBL1145629
NAs.000769 8 all-match Adenosine receptors; A1 & A3 NAs.000769 Other = 1.8 None Selectivity for human adenosine A3 receptor over human adenosine A1 receptor CHEMBL1145629
NAs.001979 2 all-match Adenosine A1 receptor NAs.001979 Ki = 74.0 nM Binding affinity for adenosine A1 receptor as inhibition of 3[H]-R-PIA binding in rat brain CHEMBL1130877
NAs.001979 2 all-match Adenosine A2a receptor NAs.001979 Ki = 4650.0 nM Binding affinity for adenosine A2a receptor as inhibition of 3[H]-CGS 21680 binding in rat striatum CHEMBL1130877
NAs.001979 2 all-match Adenosine A3 receptor NAs.001979 Ki = 26.0 nM Binding affinity for adenosine A3 receptor as inhibition of [125I]AB-MECA binding to human receptor expressed in HEK 293 cells CHEMBL1130877
NAs.002282 2 all-match Adenosine A2a receptor NAs.002282 Ki > 10000.0 nM Binding affinity for adenosine A2a receptor as inhibition of 3[H]-CGS 21680 binding in rat striatum CHEMBL1130877
NAs.002282 2 all-match Adenosine A1 receptor NAs.002282 Ki = 1230.0 nM Binding affinity for adenosine A1 receptor as inhibition of 3[H]-R-PIA binding in rat brain CHEMBL1130877
NAs.002282 2 all-match Adenosine A3 receptor NAs.002282 Ki = 20.0 nM Binding affinity for adenosine A3 receptor as inhibition of [125I]AB-MECA binding to human receptor expressed in HEK 293 cells CHEMBL1130877