Showing 1 to 8 of 8 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 Other = 0.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 Other = 0.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 Other = 0.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 Other = 0.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 Other = 0.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.000033 2 all-match Unchecked NAs.000033 Other = 12.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.000033 2 all-match Oryctolagus cuniculus NAs.000033 Other = 50.0 ug ml-1 Antiviral activity against HSV-1 cell line (concentration required to prevent viral cytopathic effect in half of primary rabbit kidney cell cultures) CHEMBL1124020
NAs.000033 2 all-match Oryctolagus cuniculus NAs.000033 Other = 50.0 ug ml-1 Antiviral activity against HSV-2 cell line (concentration required to prevent viral cytopathic effect in half of primary rabbit kidney cell cultures) CHEMBL1124020