Showing 1 to 13 of 13 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000034 2 ribose-match Adenosine A1 receptor NAs.000034 Ki = 1870.0 nM Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells CHEMBL1142938
NAs.000034 2 ribose-match Adenosine A2a receptor NAs.000034 Ki = 1780.0 nM Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cells CHEMBL1142938
NAs.000034 2 ribose-match Adenosine A3 receptor NAs.000034 Ki = 4.3 nM Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cells CHEMBL1142938
NAs.000034 2 ribose-match Adenosine receptors; A1 & A3 NAs.000034 Other = 435.0 None Selectivity for human adenosine A3 receptor over human adenosine A1 receptor CHEMBL1142938
NAs.000034 2 ribose-match Adenosine receptors; A2a & A3 NAs.000034 Other = 414.0 None Selectivity for human adenosine A3 receptor over human adenosine A2A receptor CHEMBL1142938
NAs.001943 2 ribose-match Adenosine A1 receptor NAs.001943 Ki = 53800.0 nM Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells CHEMBL1154633
NAs.001943 2 ribose-match Adenosine A2a receptor NAs.001943 Ki = 10400.0 nM Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cells CHEMBL1154633
NAs.001943 2 ribose-match Adenosine A3 receptor NAs.001943 Ki = 2.5 nM Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cells CHEMBL1154633
NAs.001943 2 ribose-match Adenosine receptors; A1 & A3 NAs.001943 Other = 21500.0 None Selectivity ratio of Ki for human recombinant adenosine A1 receptor to Ki for human recombinant adenosine A3 receptor CHEMBL1154633
NAs.001943 2 ribose-match Unchecked NAs.001943 Other = 4200.0 None Selectivity ratio of Ki for human recombinant adenosine A2A receptor to Ki for human recombinant adenosine A3 receptor CHEMBL1154633
NAs.001943 2 ribose-match Adenosine A3 receptor NAs.001943 EC50 = 112.0 nM Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 mins before addition of Eu-GTP measured after 45 mins by time-resolved fluorometric method CHEMBL1154633
NAs.001943 2 ribose-match Adenosine A3 receptor NAs.001943 Other = 100.0 % Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 mins before addition of Eu-GTP measured after 45 mins by time-resolved fluorometric method relative to Cl-IBMECA CHEMBL1154633
NAs.001943 2 ribose-match Adenosine A3 receptor NAs.001943 Other None None None Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 mins before addition of Eu-GTP measured after 45 mins by time-resolved fluorometric method in presence of increasing saponin concentration CHEMBL1154633