Showing 1 to 13 of 13 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000042 2 all-match Adenosine A1 receptor NAs.000042 Ki = 3600.0 nM Ability to displace specific radioligand [3H]R-PIA binding at Adenosine A1 receptor in rat brain membrane CHEMBL1134070
NAs.000042 2 all-match Adenosine A2a receptor NAs.000042 Other = 45.0 % Displacement of [3H]-CGS- 21680 from A2A receptors (rA2A) in rat striatal membranes at 100 uM CHEMBL1134070
NAs.000042 2 all-match Adenosine A3 receptor NAs.000042 Ki = 1090.0 nM Ability to displace specific radioligand [125I]AB-MECA binding at human Adenosine A3 receptor expressed in CHO cells CHEMBL1134070
NAs.000042 2 all-match Adenosine A1 receptor NAs.000042 EC50 = 2280.0 nM Agonist efficacy as effective concentration to stimulate binding of [35S]GTP-gamma-S, at human Adenosine A1 receptor CHEMBL1134070
NAs.000042 2 all-match Adenosine A1 receptor NAs.000042 Other = 40.0 % Efficacy to stimulate binding of [35S]GTP-gamma-S, at human Adenosine A1 receptor CHEMBL1134070
NAs.001397 2 all-match Adenosine A1 receptor NAs.001397 Ki = 5110.0 nM Ability to displace specific radioligand [3H]R-PIA binding at Adenosine A1 receptor in rat brain membrane CHEMBL1134070
NAs.001397 2 all-match Adenosine A2a receptor NAs.001397 Other = 15.0 % Displacement of [3H]-CGS- 21680 from A2A receptors (rA2A) in rat striatal membranes at 100 uM CHEMBL1134070
NAs.001397 2 all-match Adenosine A3 receptor NAs.001397 Ki = 2880.0 nM Ability to displace specific radioligand [125I]AB-MECA binding at human Adenosine A3 receptor expressed in CHO cells CHEMBL1134070
NAs.001397 2 all-match Adenosine A1 receptor NAs.001397 EC50 = 2890.0 nM Agonist efficacy as effective concentration to stimulate binding of [35S]GTP-gamma-S, at human A1 adenosine receptor CHEMBL1134070
NAs.001397 2 all-match Adenosine A1 receptor NAs.001397 Other = 30.0 % Efficacy to stimulate binding of [35S]GTP-gamma-S, at human Adenosine A1 receptor CHEMBL1134070
NAs.002945 8 ribose-match Adenosine A1 receptor NAs.002945 Ki = 8730.0 nM Ability to displace specific radioligand [3H]R-PIA binding at Adenosine A1 receptor in rat brain membrane CHEMBL1134070
NAs.002945 8 ribose-match Adenosine A2a receptor NAs.002945 Ki = 25400.0 nM Ability to displace specific radioligand [3H]-CGS- 21680 binding at A2A receptors (rA2A) in rat brain membrane CHEMBL1134070
NAs.002945 8 ribose-match Adenosine A3 receptor NAs.002945 Ki = 912.0 nM Ability to displace specific radioligand [125I]AB-MECA binding at human Adenosine A3 receptor expressed in CHO cells CHEMBL1134070