Showing 1 to 7 of 7 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000045 8 ribose-match Adenosine A1 receptor NAs.000045 Other = 6.0 % Displacement of [3H]R-PIA from human recombinant adenosine A1 receptor expressed in CHO cells at 10 uM after 60 mins by liquid scintillation counting CHEMBL2062514
NAs.000045 8 ribose-match Adenosine A2a receptor NAs.000045 Other = 38.0 % Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting CHEMBL2062514
NAs.000045 8 ribose-match Adenosine A3 receptor NAs.000045 Ki = 6.75 nM Displacement of [3H]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting CHEMBL2062514
NAs.000045 8 ribose-match Adenosine A3 receptor NAs.000045 Other = 86.7 % Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM incubated for 30 mins prior to forskolin-stimulation measured after 15 mins by enzyme immunoassay relative to NECA CHEMBL2062514
NAs.000045 8 ribose-match Adenosine A1 receptor NAs.000045 Other = 18.0 % Displacement of [3H]CGS21680 from mouse adenosine A1 receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting CHEMBL2062514
NAs.000045 8 ribose-match Adenosine A2a receptor NAs.000045 Other = 22.0 % Displacement of [3H]I-AB-MECA from mouse adenosine A2A receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting CHEMBL2062514
NAs.000045 8 ribose-match Adenosine A3 receptor NAs.000045 Ki = 3.66 nM Displacement of [3H]CGS21680 from mouse adenosine A3 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting CHEMBL2062514