| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.000146 | 2 | all-match | Human immunodeficiency virus type 1 reverse transcriptase |  |
IC50 | = | 2000.0 | nM | Inhibition of DNA synthesis by HIV reverse transcriptase | CHEMBL1135574 | |
| NAs.000146 | 2 | all-match | MT4 | |
Other | = | 131.0 | uM | The concentration required to cause a 50% inhibition of cell proliferation was determined in MT-4 cell culture. | CHEMBL1135574 | |
| NAs.000146 | 2 | all-match | MT4 | |
Other | = | 2.0 | uM | The concentration required to cause a 50% inhibition of HIV reproduction was determined in MT-4 cell culture for free forms | CHEMBL1135574 | |
| NAs.000146 | 2 | all-match | MT4 | |
Other | = | 1.2 | uM | The concentration required to cause a 50% inhibition of HIV reproduction was determined in MT-4 cell culture for liposome-entrapped forms. | CHEMBL1135574 | |
| NAs.000146 | 2 | all-match | Human immunodeficiency virus 1 | |
IC50 | = | 2000.0 | nM | Antiviral activity against HIV1 | CHEMBL1136837 | |