Showing 1 to 19 of 19 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000503 2 all-match K562 NAs.000503 IC50 = 60000.0 nM Tested for inhibition of growth in human erythroleukemia K-562 cells. CHEMBL1130411
NAs.000503 2 all-match Unchecked NAs.000503 Other = 0.8 % Percentage of benzidine positive cells is divided by the concentration used. CHEMBL1130108
NAs.000503 2 all-match K562 NAs.000503 Other = 45.0 % The ability to induce differentiation in K562 cells was estimated by determining the fraction of benzidine positive cells converted following incubation with the compound. CHEMBL1130108
NAs.000503 2 all-match K562 NAs.000503 Other = 60.0 uM The concentration used. CHEMBL1130108
NAs.000503 2 all-match Unchecked NAs.000503 Other = 0.6 % Percentage of benzidine positive cells is divided by the concentration used. CHEMBL1130108
NAs.000503 2 all-match K562 NAs.000503 Other = 15.0 uM The concentration used to induce differentiation in K562 cells CHEMBL1130108
NAs.000503 2 all-match K562 NAs.000503 IC50 = 68000.0 nM Antiproliferative activity against K562 erythroid leukemic cells was determined. CHEMBL1130108
NAs.000503 2 all-match K562 NAs.000503 Other = 9.5 % The ability to induce differentiation in K562 cells was estimated by determining the fraction of benzidine positive cells converted following incubation with the compound. CHEMBL1130108
NAs.000503 2 all-match K562 NAs.000503 Other = 17.0 % Differentiation of K-562 cells at 120 uM with coadministration of guanosine CHEMBL1130411
NAs.000503 2 all-match K562 NAs.000503 Other = 75.0 % Differentiation of K-562 cells at 120 uM with out coadministration of guanosine CHEMBL1130411
NAs.000503 2 all-match K562 NAs.000503 Other = 15.0 % Differentiation of K-562 cells at 60 uM with coadministration of guanosine CHEMBL1130411
NAs.000503 2 all-match K562 NAs.000503 Other = 45.0 % Differentiation of K-562 cells at 60 uM with out coadministration of guanosine CHEMBL1130411
NAs.000503 2 all-match K562 NAs.000503 Other = 90.0 % Inhibition of growth in human erythroleukemia K-562 cells (% of untreated control) CHEMBL1130411
NAs.000503 2 all-match Inosine-5'-monophosphate dehydrogenase 2 NAs.000503 IC50 = 800.0 nM The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 CHEMBL1130108
NAs.003153 2 all-match K562 NAs.003153 Other = 9.5 % Compound effect on differentiation of K562 cells, % of benzidine positive cells at 15 uM CHEMBL1135710
NAs.003153 2 all-match Inosine-5'-monophosphate dehydrogenase 1 NAs.003153 Ki = 660.0 nM Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I) CHEMBL1135710
NAs.003153 2 all-match Inosine-5'-monophosphate dehydrogenase 2 NAs.003153 Ki = 950.0 nM Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) CHEMBL1135710
NAs.003153 2 all-match K562 NAs.003153 IC50 = 60000.0 nM Concentration of the Antiproliferative compound required for the 50% inhibition of Growth against K562 cells CHEMBL1135710
NAs.003153 2 all-match K562 NAs.003153 Other = 0.6 % Compound effect on differentiation of K562 cells, % of benzidine positive cells at 1.0 uM CHEMBL1135710