| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.000516 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 1 |  |
Ki | = | 87.0 | nM | Inhibition of human IMPDH1 | CHEMBL1145329 | |
| NAs.000516 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 2 | |
Ki | = | 60.0 | nM | Inhibition of human IMPDH2 | CHEMBL1145329 | |
| NAs.002216 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 1 |  |
Ki | = | 87.0 | nM | Inhibition of human IMPDH1 by Spectrophotometry | CHEMBL1681750 | |
| NAs.002216 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 2 | |
Ki | = | 60.0 | nM | Inhibition of human IMPDH2 by Spectrophotometer | CHEMBL1681750 | |
| NAs.002216 | 2 | all-match | K562 | |
IC50 | = | 118400.0 | nM | Antiproliferative activity against human K562 cells after 72 hrs by MTS assay | CHEMBL1681750 | |