| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.001092 | 2 | all-match | S-adenosylmethionine synthetase gamma form |  |
Ki | = | 16000.0 | nM | Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable substrate (60 uM) | CHEMBL1123194 | |
| NAs.001092 | 2 | all-match | S-adenosylmethionine synthetase (MAT 1 and MAT 2) | |
Ki | = | 26000.0 | nM | Inhibition constant was evaluated with kidney (MAT-2) form of rat methionine adenosyltransferase, when methionine was the variable substrate (2 mM) | CHEMBL1123194 | |
| NAs.001092 | 2 | all-match | S-adenosylmethionine synthetase (MAT 1 and MAT 2) | |
Ki | = | 11000.0 | nM | Inhibition constant was evaluated on novikoff hepatoma (MAT-T) form of rat methionine adenosyltransferase, when ATP was the variable substrate (60 uM) | CHEMBL1123194 | |
| NAs.001092 | 2 | all-match | S-adenosylmethionine synthetase (MAT 1 and MAT 2) | |
Ki | = | 38000.0 | nM | Inhibition constant was evaluated on novikoff hepatoma (MAT-T) form of rat methionine adenosyltransferase, when methionine was the variable substrate (2 mM) | CHEMBL1123194 | |