Showing 1 to 10 of 10 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.001437 2 all-match Inosine-5'-monophosphate dehydrogenase 2 NAs.001437 Ki = 380.0 nM Inhibition of human IMPDH2 CHEMBL1177707
NAs.001437 2 all-match Unchecked NAs.001437 Ki > 100000.0 nM Inhibition of N-terminal His-tagged Mycobacterium tuberculosis H37Rv IMPDH CHEMBL1177707
NAs.001437 2 all-match Inosine-5'-monophosphate dehydrogenase 1 NAs.001437 Ki = 520.0 nM Inhibition of human IMPDH1 CHEMBL1177707
NAs.001925 2 all-match Inosine-5'-monophosphate dehydrogenase 1 NAs.001925 Ki = 520.0 nM Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I) CHEMBL1135710
NAs.001925 2 all-match Inosine-5'-monophosphate dehydrogenase 2 NAs.001925 Ki = 380.0 nM Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) CHEMBL1135710
NAs.001925 2 all-match K562 NAs.001925 IC50 = 100.0 nM Concentration of the Antiproliferative compound required for the 50% inhibition of Growth against K562 cells CHEMBL1135710
NAs.001925 2 all-match K562 NAs.001925 Other = 95.0 % Compound effect on differentiation of K562 cells, % of benzidine positive cells at 1.5 uM CHEMBL1135710
NAs.001925 2 all-match K562 NAs.001925 Other = 63.3 % Compound effect on differentiation of K562 cells, % of benzidine positive cells at 1.0 uM CHEMBL1135710
NAs.001925 2 all-match Inosine-5'-monophosphate dehydrogenase 1 NAs.001925 Ki = 520.0 nM Inhibition of human IMPDH1 CHEMBL1145329
NAs.001925 2 all-match Inosine-5'-monophosphate dehydrogenase 2 NAs.001925 Ki = 380.0 nM Inhibition of human IMPDH2 CHEMBL1145329