Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Type
|
Relation
|
Value
|
Unit
|
||||||||
NAs.001624 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 1 | ![]() |
Ki | = | 95.0 | nM | Inhibition of human IMPDH1 by Spectrophotometry | CHEMBL1681750 | |
NAs.001624 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 2 | ![]() |
Ki | = | 84.0 | nM | Inhibition of human IMPDH2 by Spectrophotometer | CHEMBL1681750 | |
NAs.001624 | 2 | all-match | K562 | ![]() |
IC50 | = | 10500.0 | nM | Antiproliferative activity against human K562 cells after 72 hrs by MTS assay | CHEMBL1681750 | |
NAs.003102 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 1 | ![]() |
Ki | = | 99.0 | nM | Inhibition of human IMPDH1 by Spectrophotometry | CHEMBL1681750 | |
NAs.003102 | 2 | all-match | Inosine-5'-monophosphate dehydrogenase 2 | ![]() |
Ki | = | 73.0 | nM | Inhibition of human IMPDH2 by Spectrophotometer | CHEMBL1681750 | |
NAs.003102 | 2 | all-match | K562 | ![]() |
IC50 | = | 4000.0 | nM | Antiproliferative activity against human K562 cells after 72 hrs by MTS assay | CHEMBL1681750 |