| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.001941 | 4 | all-match | Inosine-5'-monophosphate dehydrogenase 2 |  |
IC50 | = | 175000.0 | nM | The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 | CHEMBL1130108 | |
| NAs.001941 | 4 | all-match | K562 | |
IC50 | None | None | nM | Antiproliferative activity against K562 erythroid leukemic cells was determined; NE=no effect | CHEMBL1130108 | |
| NAs.001941 | 4 | all-match | K562 | |
Other | = | 75.0 | PuM | The concentration used to induce differentiation in K562 cells | CHEMBL1130108 | |
| NAs.001941 | 4 | all-match | K562 | |
Other | = | 9.0 | % | The ability to induce differentiation in K562 cells was estimated by determining the fraction of benzidine positive cells converted following incubation with the compound. | CHEMBL1130108 | |
| NAs.001941 | 4 | all-match | Unchecked | |
Other | = | 0.1 | % | Percentage of benzidine positive cells is divided by the concentration used. | CHEMBL1130108 | |