Showing 1 to 17 of 17 entries Per page:
Compound ID
Cluster
Compound Type
Target/Cell Structure Activity Assay Description Source
Type
Relation
Value
Unit
NAs.002027 2 all-match Adenosine deaminase NAs.002027 Other = 160000.0 nM Michaelis rate constant is determined by the Lineweaver and Burk method against adenosine deaminase CHEMBL1134666
NAs.002027 2 all-match Unchecked NAs.002027 Other > 21.0 % Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 250 mk/kg/day CHEMBL1134666
NAs.002027 2 all-match Unchecked NAs.002027 Other = 16.0 % Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 100 mk/kg/day CHEMBL1134666
NAs.002027 2 all-match Unchecked NAs.002027 Other = 19.3 % Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 150 mk/kg/day CHEMBL1134666
NAs.002027 2 all-match Unchecked NAs.002027 Other > 21.0 % Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 250 mk/kg/day CHEMBL1134666
NAs.002027 2 all-match CCRF-CEM NAs.002027 IC50 > 300.0 ug.mL-1 Cellular toxic effect was determined in CEM cells CHEMBL1134666
NAs.002027 2 all-match MT4 NAs.002027 IC50 = 298.0 ug.mL-1 Cellular toxic effect was determined in MT-4 cells CHEMBL1134666
NAs.002027 2 all-match Unchecked NAs.002027 Other = 19.5 % Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 150 mk/kg/day CHEMBL1134666
NAs.002027 2 all-match Moloney murine sarcoma virus NAs.002027 IC50 = 17.0 ug.mL-1 Inhibition of antiviral activity against moloney murine sarcoma virus(MSV)in CEM cells in cell protection assay CHEMBL1134666
NAs.002027 2 all-match Human immunodeficiency virus 1 NAs.002027 IC50 = 5.9 ug.mL-1 Inhibition of cytopathogenicity against human HIV-1(IIIB) in MT-4 cells CHEMBL1134666
NAs.002027 2 all-match Phosphoribosyl pyrophosphate synthetase-associated protein 2 NAs.002027 Ki = 790000.0 nM Inhibitory activity against PRPP synthetase CHEMBL1134666
NAs.002027 2 all-match Phosphoribosyl pyrophosphate synthetase-associated protein 2 NAs.002027 Other = 12.0 None Maximum velocity constant of the rate of phosphorylation was determined against PRPP synthetase CHEMBL1134666
NAs.002027 2 all-match Phosphoribosyl pyrophosphate synthetase-associated protein 2 NAs.002027 Other = 570000.0 nM Michaelis rate constant is determined by the Lineweaver and Burk method against PRPP synthetase CHEMBL1134666
NAs.002027 2 all-match Adenosine deaminase NAs.002027 Ki = 100000.0 nM Inhibitory activity against adenosine deaminase CHEMBL1134666
NAs.002027 2 all-match Adenosine deaminase NAs.002027 Other = 9.8 None Maximum velocity constant of the rate of deamination was determined against adenosine deaminase CHEMBL1134666
NAs.002027 2 all-match Human immunodeficiency virus 2 NAs.002027 IC50 = 6.4 ug.mL-1 Inhibition of cytopathogenicity against human HIV-2(LAV-2) in MT-4 cells CHEMBL1134666
NAs.002027 2 all-match Unchecked NAs.002027 Other > 21.0 % Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 100 mk/kg/day CHEMBL1134666