| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.002159 | 6 | all-match | Human immunodeficiency virus type 1 reverse transcriptase |  |
Ki | = | 230.0 | nM | Inhibition of HIV1 reverse transcriptase by steady state nucleotide incorporation assay | CHEMBL1155161 | |
| NAs.002159 | 6 | all-match | Human immunodeficiency virus type 1 reverse transcriptase | |
Other | = | 0.51 | None | Ratio of Ki to Km for HIV1 reverse transcriptase by steady state nucleotide incorporation assay | CHEMBL1155161 | |
| NAs.002159 | 6 | all-match | Human immunodeficiency virus type 1 reverse transcriptase | |
Ki | = | 150.0 | nM | Inhibition of HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant by steady state nucleotide incorporation assay | CHEMBL1155161 | |
| NAs.002159 | 6 | all-match | Unchecked | |
Other | = | 0.65 | None | Ratio of Ki for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant to Ki for wild-type reverse transcriptase | CHEMBL1155161 | |
| NAs.002159 | 6 | all-match | Human immunodeficiency virus type 1 reverse transcriptase | |
Other | = | 0.26 | None | Ratio of Ki to Km for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant by steady state nucleotide incorporation assay | CHEMBL1155161 | |
| NAs.002159 | 6 | all-match | Unchecked | |
Other | = | 0.5 | None | Ratio of Ki/Km for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant to Ki/Km for wild-type reverse transcriptase | CHEMBL1155161 | |