| Compound ID |
Cluster
|
Compound Type
|
Target/Cell | Structure | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.002501 | 7 | all-match | Adenosine deaminase |  |
Other | > | 800000.0 | nM | Michaelis rate constant is determined by the Lineweaver and Burk method against adenosine deaminase | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Adenosine deaminase | |
Ki | > | 800000.0 | nM | Inhibitory activity against adenosine deaminase | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Human immunodeficiency virus 1 | |
IC50 | = | 1.4 | ug.mL-1 | Inhibition of cytopathogenicity against human HIV-1(IIIB) in MT-4 cells | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Human immunodeficiency virus 2 | |
IC50 | = | 1.0 | ug.mL-1 | Inhibition of cytopathogenicity against human HIV-2(LAV-2) in MT-4 cells | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Moloney murine sarcoma virus | |
IC50 | = | 0.93 | ug.mL-1 | Inhibition of antiviral activity against moloney murine sarcoma virus(MSV)in CEM cells in cell protection assay | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | MT4 | |
IC50 | = | 265.0 | ug.mL-1 | Cellular toxic effect was determined in MT-4 cells | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | CCRF-CEM | |
IC50 | = | 280.0 | ug.mL-1 | Cellular toxic effect was determined in CEM cells | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Unchecked | |
Other | > | 21.0 | % | Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 250 mk/kg/day | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Unchecked | |
Other | > | 21.0 | % | Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 150 mk/kg/day | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Unchecked | |
Other | > | 21.0 | % | Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 100 mk/kg/day | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Unchecked | |
Other | > | 21.0 | % | Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 250 mk/kg/day | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Unchecked | |
Other | > | 21.0 | % | Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 150 mk/kg/day | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Unchecked | |
Other | > | 21.0 | % | Inhibitory effects on HSV-1 induced mortality in NMRI mice upon (ip) administration at a dose of 100 mk/kg/day | CHEMBL1134666 | |
| NAs.002501 | 7 | all-match | Mus musculus | |
Other | = | 710.0 | mg.kg-1 | lethal dose was determined | CHEMBL1134666 | |