显示 1 到 50 条，共 2289 条数据 每页数据量:
Compound ID
Cluster
Compound Type
Target Name Img Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000000 2 ribose-match Adenosine receptors; A1 & A2 NAs.000000 Ratio = 2.4 None Selectivity ratio for A1 receptor to that of A2 receptor in vitro in rat tissues CHEMBL1124694
NAs.000000 2 ribose-match Adenosine receptors; A1 & A2 NAs.000000 Ratio = 2.4 None Ratio of Ki at adenosine A2 and A1 receptors CHEMBL1124304
NAs.000009 8 ribose-match Adenosine receptors; A1 & A3 NAs.000009 FC > 20.0 None Selectivity for human recombinant adenosine A3 receptor over human recombinant adenosine A1 receptor CHEMBL1154768
NAs.000012 2 all-match Adenosine receptors; A1 & A2a NAs.000012 Ratio > 333.0 None Relative affinities against adenosine A2A and A1 receptors (ratio of KiA2A/KiA1) CHEMBL1144357
NAs.000012 2 all-match Adenosine receptors; A1 & A3 NAs.000012 Ratio = 85.3 None Relative affinities for adenosine A3 and A1 receptors (ratio of KiA3/KiA1) CHEMBL1144357
NAs.000012 2 all-match Adenosine receptors; A2a & A3 NAs.000012 Ratio > 3.9 None Relative affinities for adenosine A2A and A3 receptors (ratio of KiA2A/KiA3) CHEMBL1144357
NAs.000015 2 all-match Adenosine receptors; A1 & A3 NAs.000015 Ratio Ki = 18.0 None Selectivity for human adenosine A3 receptor over human adenosine A1 receptor CHEMBL1142938
NAs.000015 2 all-match Adenosine receptors; A2a & A3 NAs.000015 Ratio Ki = 140.0 None Selectivity for human adenosine A3 receptor over human adenosine A2A receptor CHEMBL1142938
NAs.000016 7 ribose-match Adenosine receptors; A1 & A3 NAs.000016 Ratio Ki = 19.0 None Selectivity index, ratio of Ki for recombinant human adenosine A3 receptor to Ki for recombinant human adenosine A1 receptor CHEMBL4152191
NAs.000026 2 ribose-match Adenosine receptors; A2a & A3 NAs.000026 Selectivity = 100.0 None Ratio of binding to adenosine A2a and adenosine A3 receptor CHEMBL1138752
NAs.000026 2 ribose-match Adenosine receptors; A1 & A3 NAs.000026 Selectivity = 90.0 None Ratio of binding to adenosine A1 and adenosine A3 receptor CHEMBL1138752
NAs.000029 7 all-match Adenosine receptors; A1 & A2a NAs.000029 Selectivity = 0.01 None Selective binding affinity towards human Adenosine A1 receptor expressed in CHO cells using [3H]DPCPX compared to human Adenosine A2a receptor expressed in HEK293 cells using [3H]-CGS-21,680 CHEMBL1140374
NAs.000034 2 ribose-match Adenosine receptors; A1 & A3 NAs.000034 Ratio Ki = 435.0 None Selectivity for human adenosine A3 receptor over human adenosine A1 receptor CHEMBL1142938
NAs.000034 2 ribose-match Adenosine receptors; A2a & A3 NAs.000034 Ratio Ki = 414.0 None Selectivity for human adenosine A3 receptor over human adenosine A2A receptor CHEMBL1142938
NAs.000036 7 all-match Adenosine receptors; A1 & A2a NAs.000036 Selectivity = 0.15 None Selective binding affinity towards human Adenosine A1 receptor expressed in CHO cells using [3H]DPCPX compared to human Adenosine A2a receptor expressed in HEK293 cells using [3H]-CGS-21,680 CHEMBL1140374
NAs.000040 7 ribose-match Adenosine receptors; A1 & A3 NAs.000040 Ratio = 0.0051 None Ratio of the binding affinities against rat brain A1 and A3 receptors, KiA1/KiA3. CHEMBL1128362
NAs.000041 2 all-match Adenosine receptors; A1 & A2 NAs.000041 Selectivity = 19.0 None Selectivity determined as Ratio of Ki(nM) of A1 adenosine receptor to the Ki(nM) of A2 adenosine receptor CHEMBL1125505
NAs.000041 2 all-match Adenosine receptors; A1 & A2 NAs.000041 Selectivity = 16.7 None Selectivity against adenosine A1 to A2 receptors CHEMBL1126140
NAs.000041 2 all-match Adenosine receptors; A1 & A2 NAs.000041 Selectivity = 17.0 None Selectivity for adenosine receptor subtype, ratio of Ki(nM) at A1 receptor to Ki(nM) at A2 receptor CHEMBL1126082
NAs.000041 2 all-match Adenosine receptors; A1 & A2 NAs.000041 A2 selectivity = 4.0 None Selectivity as A1 adenosine receptors(high affinity) using [3H]CCPA compared to A2 adenosine receptors using [3H]-NECA in rat striatal membranes CHEMBL1126089
NAs.000041 2 all-match Adenosine receptors; A1 & A2 NAs.000041 A2 selectivity = 3.0 None Selectivity as A1 adenosine receptors(high affinity) using [3H]-DPCPX compared to A2 adenosine receptors using [3H]NECA in rat striatal membranes CHEMBL1126089
NAs.000041 2 all-match Adenosine receptors; A1 & A2 NAs.000041 Ratio = 0.057 None Ratio of A2 to A1. CHEMBL1125572
NAs.000044 2 ribose-match Adenosine receptors; A1 & A3 NAs.000044 Ratio = 13.0 None Ratio of Ki for A1 and A3 receptors CHEMBL1127377
NAs.000044 2 ribose-match Adenosine receptors; A1 & A3 NAs.000044 Ratio = 13.0 None Relative binding affinity for Adenosine A1 and A3 receptors CHEMBL1133730
NAs.000051 7 ribose-match Adenosine receptors; A1 & A3 NAs.000051 Ratio Ki = 18.0 None Selectivity index, ratio of Ki for recombinant human adenosine A3 receptor to Ki for recombinant human adenosine A1 receptor CHEMBL4152191
NAs.000052 7 ribose-match Adenosine receptors; A2a & A2b NAs.000052 Selectivity = 45.81 None Selective binding affinity towards human Adenosine A2b receptor expressed in HEK293 cells using [3H]-DPCPX compared to human Adenosine A2a receptor expressed in HEK293 cells using [3H]CGS-21680 CHEMBL1140374
NAs.000052 7 ribose-match Adenosine receptors; A1 & A2a NAs.000052 Selectivity = 7.84 None Selective binding affinity towards human Adenosine A1 receptor expressed in CHO cells using [3H]DPCPX compared to human Adenosine A2a receptor expressed in HEK293 cells using [3H]-CGS-21,680 CHEMBL1140374
NAs.000059 7 all-match Adenosine receptors; A1 & A3 NAs.000059 Ratio = 0.099 None Ratio of the binding affinities against rat brain A1 and A3 receptors, KiA1/KiA3. CHEMBL1128362
NAs.000060 2 ribose-match Adenosine receptors; A1 & A3 NAs.000060 Ratio Ki = 710.0 None Selectivity for adenosine A1 receptor over adenosine A3 receptor CHEMBL1146258
NAs.000062 2 all-match Adenosine receptors; A1 & A2 NAs.000062 Selectivity = 42.0 None Selectivity determined as Ratio of Ki(nM) of A1 adenosine receptor to the Ki(nM) of A2 adenosine receptor CHEMBL1125505
NAs.000064 2 ribose-match Adenosine receptors; A1 & A2 NAs.000064 Ratio = 21.0 None Ratio of IC50 values for A1 receptor binding to that of A2 receptor CHEMBL1125861
NAs.000070 8 ribose-match Adenosine receptors; A1 & A3 NAs.000070 Selectivity ratio > 400.0 None Selectivity for human adenosine A3 receptor over human adenosine A1 receptor CHEMBL1159060
NAs.000072 2 all-match Adenosine receptors; A1 & A2 NAs.000072 Selectivity = 45.0 None Selectivity for adenosine receptor subtype, ratio of Ki(nM) at A1 receptor to Ki(nM) at A2 receptor CHEMBL1126082
NAs.000072 2 all-match Adenosine receptors; A1 & A2 NAs.000072 Selectivity = 43.0 None Selectivity determined as Ratio of Ki(nM) of A1 adenosine receptor to the Ki(nM) of A2 adenosine receptor CHEMBL1125505
NAs.000072 2 all-match Adenosine receptors; A1 & A2 NAs.000072 Selectivity = 45.0 None Selectivity against adenosine A1 to A2 receptors CHEMBL1126140
NAs.000072 2 all-match Adenosine receptors; A1 & A2 NAs.000072 Ratio = 0.028 None Ratio of A2 to A1. CHEMBL1125572
NAs.000072 2 all-match Adenosine receptors; A2a & A3 NAs.000072 Ratio = 1.0 None Selectivity ratio of Ki at A2A adenosine receptor to Ki at A3 adenosine receptor CHEMBL1135517
NAs.000072 2 all-match Adenosine receptors; A1 & A2 NAs.000072 A2 selectivity = 3.0 None Selectivity as A1 adenosine receptors(high affinity) using [3H]-DPCPX compared to A2 adenosine receptors using [3H]NECA in rat striatal membranes CHEMBL1126089
NAs.000072 2 all-match Adenosine receptors; A1 & A2a NAs.000072 Ratio = 49.0 None Relative affinities for Adenosine A1 and A2A receptors CHEMBL1129447
NAs.000072 2 all-match Adenosine receptors; A1 & A3 NAs.000072 Ratio = 4.0 None Selectivity ratio of Ki at A1 adenosine receptor to Ki at A3 adenosine receptor CHEMBL1135517
NAs.000072 2 all-match Adenosine receptors; A1 & A2 NAs.000072 A2 selectivity = 4.0 None Selectivity as A1 adenosine receptors(high affinity) using [3H]CCPA compared to A2 adenosine receptors using [3H]-NECA in rat striatal membranes CHEMBL1126089
NAs.000073 2 ribose-match Adenosine receptors; A1 & A3 NAs.000073 Ratio = 0.2 None Selectivity ratio of Ki at A1 adenosine receptor to Ki at A3 adenosine receptor CHEMBL1135517
NAs.000073 2 ribose-match Adenosine receptors; A2a & A3 NAs.000073 Ratio = 2.0 None Selectivity ratio of Ki at A2A adenosine receptor to Ki at A3 adenosine receptor CHEMBL1135517
NAs.000073 2 ribose-match Adenosine receptors; A1 & A2 NAs.000073 Selectivity = 2.0 None Selectivity for adenosine receptor subtype, ratio of Ki(nM) at A1 receptor to Ki(nM) at A2 receptor CHEMBL1126082
NAs.000075 2 all-match Adenosine receptors; A1 & A3 NAs.000075 Ratio Ki = 112.8 None Selectivity for human adenosine A1 receptor over human adenosine A3 receptor CHEMBL1140761
NAs.000084 8 ribose-match Adenosine receptors; A1 & A3 NAs.000084 Selectivity ratio >= 1000.0 None Selectivity ratio of inhibition of human adenosine A1 receptor to Ki for human adenosine A3 receptor CHEMBL2086387
NAs.000085 2 ribose-match Adenosine receptors; A1 & A3 NAs.000085 Ratio Ki = 13.0 None Selectivity for adenosine A1 receptor over adenosine A3 receptor CHEMBL1146258
NAs.000086 7 ribose-match Adenosine receptors; A1 & A3 NAs.000086 Ratio Ki = 71.0 None Selectivity index, ratio of Ki for recombinant human adenosine A3 receptor to Ki for recombinant human adenosine A1 receptor CHEMBL4152191
NAs.000091 2 ribose-match Adenosine receptors; A1 & A2 NAs.000091 Ratio = 380.0 None Selectivity for A1 and A2 receptors was evaluated CHEMBL1126102
NAs.000092 2 all-match Adenosine receptors; A1 & A2 NAs.000092 Selectivity = 1.6 None Ratio between Ki values of A1 and A2 receptors was determined CHEMBL1127534