显示 1 到 50 条，共 65 条数据 每页数据量:
Compound ID
Cluster
Compound Type
Target Name Img Activity Assay Description Source
Type
Relation
Value
Unit
NAs.000056 2 all-match Catechol O-methyltransferase NAs.000056 Ki > 5400000.0 nM Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assay CHEMBL1121736
NAs.000066 2 all-match Catechol O-methyltransferase NAs.000066 Inhibition = 0.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.000066 2 all-match Catechol O-methyltransferase NAs.000066 Inhibition = 26.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 39.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 87.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 5.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 22.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 39.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 87.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 5.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 22.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 24.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.1 mM CHEMBL3272009
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 33.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.2 mM CHEMBL3272009
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Inhibition = 64.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.6 mM CHEMBL3272009
NAs.000315 2 all-match Catechol O-methyltransferase NAs.000315 Kis = 36.3 uM Inhibition of Sprague-Dawley rat liver catechol O-methyltransferase using 24 to 210 uM S-adenosylmethionine substrate CHEMBL3272184
NAs.000364 2 all-match Catechol O-methyltransferase NAs.000364 Inhibition = 42.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.000364 2 all-match Catechol O-methyltransferase NAs.000364 Inhibition = 14.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.000438 2 all-match Catechol O-methyltransferase NAs.000438 Inhibition = 9.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.000438 2 all-match Catechol O-methyltransferase NAs.000438 Inhibition = 10.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.000438 2 all-match Catechol O-methyltransferase NAs.000438 Inhibition = 3.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.000438 2 all-match Catechol O-methyltransferase NAs.000438 Inhibition = 4.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.000459 2 all-match Catechol O-methyltransferase NAs.000459 Inhibition = 0.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.000459 2 all-match Catechol O-methyltransferase NAs.000459 Inhibition = 12.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.000504 2 all-match Catechol O-methyltransferase NAs.000504 Inhibition = 5.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.000504 2 all-match Catechol O-methyltransferase NAs.000504 Inhibition = 22.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.000583 2 all-match Catechol O-methyltransferase NAs.000583 Kis = 168.0 uM Inhibition of Sprague-Dawley rat liver catechol O-methyltransferase using 24 to 210 uM S-adenosylmethionine substrate CHEMBL3272184
NAs.000583 2 all-match Catechol O-methyltransferase NAs.000583 Inhibition = 71.0 % Inhibition of Sprague-Dawley rat liver catechol O-methyltransferase using 1 mM S-adenosylmethionine substrate at 1.5 mM CHEMBL3272184
NAs.000607 2 all-match Catechol O-methyltransferase NAs.000607 Inhibition = 7.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.000607 2 all-match Catechol O-methyltransferase NAs.000607 Inhibition = 14.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.001385 2 all-match Catechol O-methyltransferase NAs.001385 Inhibition = 8.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.001385 2 all-match Catechol O-methyltransferase NAs.001385 Inhibition = 45.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.001595 2 all-match Catechol O-methyltransferase NAs.001595 Inhibition = 20.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 1.2 mM CHEMBL3272009
NAs.001595 2 all-match Catechol O-methyltransferase NAs.001595 Inhibition = 12.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.6 mM CHEMBL3272009
NAs.001595 2 all-match Catechol O-methyltransferase NAs.001595 Inhibition = 0.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.1 mM CHEMBL3272009
NAs.002124 2 all-match Catechol O-methyltransferase NAs.002124 Inhibition = 0.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.1 mM CHEMBL3272009
NAs.002124 2 all-match Catechol O-methyltransferase NAs.002124 Inhibition = 12.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.6 mM CHEMBL3272009
NAs.002124 2 all-match Catechol O-methyltransferase NAs.002124 Inhibition = 20.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 1.2 mM CHEMBL3272009
NAs.002156 2 all-match Catechol O-methyltransferase NAs.002156 Inhibition = 3.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.002156 2 all-match Catechol O-methyltransferase NAs.002156 Inhibition = 10.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.002236 2 all-match Catechol O-methyltransferase NAs.002236 Inhibition = 1.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.002236 2 all-match Catechol O-methyltransferase NAs.002236 Inhibition = 10.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.002353 2 all-match Catechol O-methyltransferase NAs.002353 Inhibition = 2.0 % Inhibition of Sprague-Dawley rat liver COMT at 0.2 mM by radiochemical technique CHEMBL3244179
NAs.002353 2 all-match Catechol O-methyltransferase NAs.002353 Inhibition = 25.0 % Inhibition of Sprague-Dawley rat liver COMT at 2 mM by radiochemical technique CHEMBL3244179
NAs.002818 2 all-match Catechol O-methyltransferase NAs.002818 Km = 44600.0 nM In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver CHEMBL1130076
NAs.002963 2 all-match Catechol O-methyltransferase NAs.002963 Inhibition = 14.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976
NAs.002963 2 all-match Catechol O-methyltransferase NAs.002963 Inhibition = 42.0 % Inhibition of Catechol O-methyltransferase at 1.0 mM CHEMBL1122976
NAs.003072 2 all-match Catechol O-methyltransferase NAs.003072 Inhibition = 11.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.6 mM CHEMBL3272009
NAs.003072 2 all-match Catechol O-methyltransferase NAs.003072 Inhibition = 19.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 1.2 mM CHEMBL3272009
NAs.003072 2 all-match Catechol O-methyltransferase NAs.003072 Inhibition = 0.0 % Inhibition of catechol O-methyltransferase (unknown origin) using 1 mM SAM as substrate at 0.1 mM CHEMBL3272009
NAs.003106 2 all-match Catechol O-methyltransferase NAs.003106 Inhibition = 0.0 % Inhibition of Catechol O-methyltransferase at 0.1 mM CHEMBL1122976