Compound ID |
Cluster
|
Compound Type
|
Target Name | Img | Activity | Assay Description | Source | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Type
|
Relation
|
Value
|
Unit
|
||||||||
NAs.000033 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.000033 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.000033 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 0.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.000033 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 0.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.000033 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 0.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.001558 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.001558 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 0.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.001558 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 0.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.001558 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 0.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.001704 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 0.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.001704 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 0.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.001704 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.001704 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.001704 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 0.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.002639 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.002639 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.002639 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 0.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.002639 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 0.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.002639 | 2 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 5.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.003443 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 0.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.003443 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 13.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.003443 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 75.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.003443 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 37.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.003443 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 3.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004349 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 90.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.004349 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 3.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004349 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 10.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004349 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 84.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004349 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 60.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.004354 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 20.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.004354 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 17.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004354 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 10.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004354 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004354 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 55.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.004356 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 17.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.004356 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 3.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004356 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 9.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004356 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 60.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004356 | 7 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 79.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.004734 | 0 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
TP | = | 0.0 | % | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004734 | 0 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
DP | = | 0.0 | % | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004734 | 0 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
Inhibition | = | 22.0 | % | Inhibition of DNA polymerase | CHEMBL1124020 | |
NAs.004734 | 0 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 0.0 | % | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | CHEMBL1124020 | |
NAs.004734 | 0 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
MP | = | 23.0 | % | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | CHEMBL1124020 | |
NAs.004750 | 6 | all-match | Human herpesvirus 1 DNA polymerase | ![]() |
IC50 | = | 3300.0 | nM | Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 degrees C | CHEMBL1141075 |