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Compound ID Target Name Img Activity Assay Description Source
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 MP = 0.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 MP = 0.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 DP = 0.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 TP = 0.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.000033 2 all-match Human herpesvirus 1 DNA polymerase NAs.000033 Inhibition = 0.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.001558 2 all-match Human herpesvirus 1 DNA polymerase NAs.001558 MP = 0.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.001558 2 all-match Human herpesvirus 1 DNA polymerase NAs.001558 DP = 0.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.001558 2 all-match Human herpesvirus 1 DNA polymerase NAs.001558 TP = 0.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.001558 2 all-match Human herpesvirus 1 DNA polymerase NAs.001558 Inhibition = 0.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.001704 2 all-match Human herpesvirus 1 DNA polymerase NAs.001704 Inhibition = 0.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.001704 2 all-match Human herpesvirus 1 DNA polymerase NAs.001704 TP = 0.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.001704 2 all-match Human herpesvirus 1 DNA polymerase NAs.001704 MP = 0.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.001704 2 all-match Human herpesvirus 1 DNA polymerase NAs.001704 MP = 0.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.001704 2 all-match Human herpesvirus 1 DNA polymerase NAs.001704 DP = 0.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.002639 2 all-match Human herpesvirus 1 DNA polymerase NAs.002639 MP = 0.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.002639 2 all-match Human herpesvirus 1 DNA polymerase NAs.002639 MP = 0.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.002639 2 all-match Human herpesvirus 1 DNA polymerase NAs.002639 DP = 0.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.002639 2 all-match Human herpesvirus 1 DNA polymerase NAs.002639 TP = 0.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.002639 2 all-match Human herpesvirus 1 DNA polymerase NAs.002639 Inhibition = 5.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.003443 7 all-match Human herpesvirus 1 DNA polymerase NAs.003443 Inhibition = 0.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.003443 7 all-match Human herpesvirus 1 DNA polymerase NAs.003443 DP = 13.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.003443 7 all-match Human herpesvirus 1 DNA polymerase NAs.003443 TP = 75.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.003443 7 all-match Human herpesvirus 1 DNA polymerase NAs.003443 MP = 37.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.003443 7 all-match Human herpesvirus 1 DNA polymerase NAs.003443 MP = 3.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004349 7 all-match Human herpesvirus 1 DNA polymerase NAs.004349 MP = 90.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.004349 7 all-match Human herpesvirus 1 DNA polymerase NAs.004349 MP = 3.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004349 7 all-match Human herpesvirus 1 DNA polymerase NAs.004349 DP = 10.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004349 7 all-match Human herpesvirus 1 DNA polymerase NAs.004349 TP = 84.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004349 7 all-match Human herpesvirus 1 DNA polymerase NAs.004349 Inhibition = 60.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.004354 7 all-match Human herpesvirus 1 DNA polymerase NAs.004354 Inhibition = 20.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.004354 7 all-match Human herpesvirus 1 DNA polymerase NAs.004354 TP = 17.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004354 7 all-match Human herpesvirus 1 DNA polymerase NAs.004354 DP = 10.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004354 7 all-match Human herpesvirus 1 DNA polymerase NAs.004354 MP = 0.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004354 7 all-match Human herpesvirus 1 DNA polymerase NAs.004354 MP = 55.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.004356 7 all-match Human herpesvirus 1 DNA polymerase NAs.004356 MP = 17.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.004356 7 all-match Human herpesvirus 1 DNA polymerase NAs.004356 MP = 3.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004356 7 all-match Human herpesvirus 1 DNA polymerase NAs.004356 DP = 9.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004356 7 all-match Human herpesvirus 1 DNA polymerase NAs.004356 TP = 60.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004356 7 all-match Human herpesvirus 1 DNA polymerase NAs.004356 Inhibition = 79.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.004734 0 all-match Human herpesvirus 1 DNA polymerase NAs.004734 TP = 0.0 % Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004734 0 all-match Human herpesvirus 1 DNA polymerase NAs.004734 DP = 0.0 % Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004734 0 all-match Human herpesvirus 1 DNA polymerase NAs.004734 Inhibition = 22.0 % Inhibition of DNA polymerase CHEMBL1124020
NAs.004734 0 all-match Human herpesvirus 1 DNA polymerase NAs.004734 MP = 0.0 % Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr CHEMBL1124020
NAs.004734 0 all-match Human herpesvirus 1 DNA polymerase NAs.004734 MP = 23.0 % Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night CHEMBL1124020
NAs.004750 6 all-match Human herpesvirus 1 DNA polymerase NAs.004750 IC50 = 3300.0 nM Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 degrees C CHEMBL1141075