| Compound ID |
Cluster
|
Compound Type
|
Target Name | Img | Activity | Assay Description | Source | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Type
|
Relation
|
Value
|
Unit
|
||||||||
| NAs.000002 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.000120 | 2 | all-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.000218 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.000223 | 7 | all-match | DNA polymerase beta |  |
IC50 | = | 23000.0 | nM | Inhibition of human DNA polymerase beta by microplate reader analysis | CHEMBL1649500 | |
| NAs.000469 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.000670 | 2 | ribose-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.000877 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.000885 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.000926 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 25118.9 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001024 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001547 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 3548.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001552 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001769 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001785 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 891.3 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001797 | 9 | all-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001799 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 3548.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001804 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 17782.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001805 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001807 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 1584.9 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001830 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 44668.4 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001836 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001837 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001852 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 8912.5 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001864 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 7943.3 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001866 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001882 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 22387.2 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001883 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001884 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001893 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.001908 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.002091 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 39810.7 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.002557 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 158.5 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.002857 | 7 | all-match | DNA polymerase beta |  |
IC50 | = | 33000.0 | nM | Inhibition of human DNA polymerase beta by microplate reader analysis | CHEMBL1649500 | |
| NAs.003185 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 19952.6 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003189 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 89125.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003191 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 22387.2 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003193 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003334 | 7 | ribose-match | DNA polymerase beta |  |
Potency | = | 70794.6 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003597 | 0 | all-match | DNA polymerase beta |  |
IC50 | > | 200000.0 | nM | Inhibition of recombinant human DNA polymerase beta preincubated with enzyme followed by addition of dATP/dGTP/TTP as substrate in presence of [gamma-33P]TTP by phosphorimaging assay | CHEMBL4007399 | |
| NAs.003635 | 2 | all-match | DNA polymerase beta |  |
Potency | = | 100000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003810 | 2 | all-match | DNA polymerase beta |  |
Potency | = | 158.5 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003852 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 10000.0 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003854 | 0 | all-match | DNA polymerase beta |  |
Inhibition | < | 50.0 | % | Inhibition of human DNA-dependent DNA polymerase beta using calf thymus DNA/[3H]dTTP as substrate by microplate scintillation reader | CHEMBL3414561 | |
| NAs.003855 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 28183.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003861 | 0 | all-match | DNA polymerase beta |  |
Inhibition | < | 50.0 | % | Inhibition of human DNA-dependent DNA polymerase beta using calf thymus DNA/[3H]dTTP as substrate by microplate scintillation reader | CHEMBL3414561 | |
| NAs.003864 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 44668.4 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003866 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 5623.4 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003867 | 7 | base-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003868 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 79432.8 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |
| NAs.003869 | 7 | all-match | DNA polymerase beta |  |
Potency | = | 3981.1 | nM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | CHEMBL1201862 | |